LARIMER COUNTY, Colo. (CBS4)- Northbound lanes of Interstate 25 reopened just before 5 p.m. after they were closed for hours on Tuesday afternoon for a multi-vehicle crash that involved semis. The closure was northbound at mile marker 255 near Thompson River Ranch, south of Loveland.

Loveland Fire Authority says more than 17 vehicles were involved; three semi tractor trailers, five large vehicles and multiple small passenger vehicles.

The anticipated closure was expected to be at least 4 hours. What caused the crash is being investigated, but it was snowing at the time and some roads were reportedly slick and icy in spots.

Six people were taken to the hospital. No fatalities according to the Colorado State Patrol.

Some southbound lanes were closed during the crash investigation and cleanup.