Parts of the Eisenhower Expressway in Chicago's western suburbs were closed early Sunday morning because of a deadly multi-vehicle crash.

Illinois State Police said troopers responded at 2:53 a.m. for a two-vehicle crash involving a Jeep and a Saturn on the outbound Eisenhower at Home Avenue. Home Avenue runs halfway between Harlem and Oak Park avenues — the equivalent of Chicago's Sayre Avenue.

One occupant was ejected from one of the vehicles and died, state police said. A second occupant was also hospitalized in an unspecified condition.

A body was spotted at the scene, along with multiple damaged cars.

Following the crash, the outbound Eisenhower was closed between Harlem and Central avenues, a stretch of two miles. 

The crash remained under investigation Sunday morning.