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In a San Francisco 49ers regular season already awash with injuries, head coach Kyle Shanahan is now facing the very real possibility that starting quarterback Jimmy Garoppolo has been lost for the remainder of the year.
As the NFL Trading Deadline came and went Tuesday afternoon, the San Francisco 49ers announced they have waived former second round pick Dante Pettis, who never fulfilled the potential on the professional level that he achieved as star receiver at the University of Washington.
In a season marred by injuries, the San Francisco 49ers were dealt two more serious blows Monday as both star tight end George Kittle and starting quarterback Jimmy Garoppolo have again been sidelined and will miss games.
The Seattle Seahawks rebounded from their first loss of the season with a resounding 37-27 win over the San Francisco 49ers on Sunday.
This week, the San Francisco 49ers don't need loud piped in noise at practice, silent counts and other preparations that usually accompany a trip to Seattle.
There's no denying there is a certain mentality that permeates the San Francisco 49ers lockerroom. It's raw, physical and creates an aggressive in-your-face mindset when the team takes the field.
Jeff Wilson Jr. rushed for a career-high three touchdowns and 112 yards before leaving with an ankle injury and the 49ers dominated in a 33-6 win over the Patriots on Sunday.
The San Francisco 49ers announced Friday they will be without starting safeties Jaquiski Tartt and Jimmie Ward for Sunday's game against the New England Patriots.
The 49ers are coming off a solid win, while the Patriots are coming off an ugly loss. Both teams need a win to keep pace in tough divisions.
The mayor of Santa Clara is accusing San Francisco 49ers owner Jed York of spending millions to support City Council candidates in the upcoming election that may give the team more favorable treatment.
Former San Francisco 49ers and Oakland Raiders defensive lineman Dana Stubblefield was sentenced Thursday to 15 to life in prison for raping a woman at gunpoint in 2015.
Once assumed to be Brady's heir apparent, Jimmy Garoppolo returns to New England Sunday to face his former team for the first time since being traded to San Francisco in 2017.
Dr. Anthony Fauci, the country's COVID-19 expert, plans to visit Santa Clara County next week and meet with local leaders to discuss the ongoing pandemic and logistics for lowering case numbers while establishing safe reopening plans.
Up until last Sunday's win over the Los Angeles Rams, the San Francisco 49ers have simply been lackluster when playing at home in front of the empty Levi's Stadium stands.
California announced new rules for outdoor stadiums Tuesday that allow for some fans to return to the stands while the COVID-19 pandemic rolls on. Sadly for San Francisco 49ers fans, there's no plans for the county to allow fans at Levi's Stadium.
The San Francisco 49ers came down from the high of beating the Los Angeles Rams on Sunday night to learn that the reigning NFC Champions will have to overcome more injuries.
New England Patriots head coach Bill Belichick has a reputation for being a man of a few words, but on Monday he had plenty to say about San Francisco 49ers star tight end George Kittle.
Jimmy Garoppolo and the San Francisco 49ers bounced back from a lopsided loss and showed the banged-up defending NFC champions aren't ready to pack it in quite yet.
Jimmy Garoppolo's sprained right ankle felt much better this week in practice, making the San Francisco 49ers confident their quarterback can bounce back from a rough performance last week that got him pulled at halftime.
Former San Francisco 49ers star defensive lineman and NFL Hall of Famer Fred Dean has passed away at the age of 68 after being hospitalized with COVID-19.
Jimmy Garoppolo returned to practice for the San Francisco 49ers Wednesday, a few days after getting pulled at halftime because of a bum ankle and bad performance.
The Miami Dolphins sent the defending NFC champion San Francisco 49ers to their third straight home loss to open the season, 43-17 on Sunday. Niners QB Jimmy Garoppolo played his worst game as a pro before getting benched.
Announcers for the Bay Area's major sports franchises have partnered to release a public service announcement to encourage people to help protect each other from the coronavirus using highlights of some the region's greatest sport plays including 'The Play' in the 1982 Cal-Stanford Big Game and 49ers great Dwight Clark's 'The Catch'.
After practicing Wednesday and Thursday, the San Francisco 49ers expect quarterback Jimmy Garoppolo to play on Sunday against the Miami Dolphins, 49ers Head Coach Kyle Shanahan announced Friday.
The San Francisco 49ers defense has again suffered a devastating injury -- veteran defensive end Ziggy Ansah has been lost with a torn bicep suffered in Sunday's loss to the Philadelphia Eagles.
The final chapter in the story of Dirt Alley was written Wednesday night as they unveiled the tiles of artwork on the pavement.
A Bay Area cancer patient is making more memories and living longer than his initial diagnosis thanks to a groundbreaking treatment for his particularly aggressive form of brain cancer.
A Peninsula pastor is one of the first in the Bay Area to help provide a safe place for them while they search for housing in expensive Silicon Valley.
The supervisor introduced the "Affordable Groceries Act," which includes two measures he hopes will get on the November ballot. One of the measures would tax large-chain grocery stores that have closed, yet are holding onto the property.
A local floral studio had the privilege of doing the floral arrangements for the "Love is You" gathering in San Francisco, an event celebrating LGBTQ+ visibility during the World Cup and Pride Month.
The final chapter in the story of Dirt Alley was written Wednesday night as they unveiled the tiles of artwork on the pavement.
A Bay Area cancer patient is making more memories and living longer than his initial diagnosis thanks to a groundbreaking treatment for his particularly aggressive form of brain cancer.
A Peninsula pastor is one of the first in the Bay Area to help provide a safe place for them while they search for housing in expensive Silicon Valley.
The supervisor introduced the "Affordable Groceries Act," which includes two measures he hopes will get on the November ballot. One of the measures would tax large-chain grocery stores that have closed, yet are holding onto the property.
A local floral studio had the privilege of doing the floral arrangements for the "Love is You" gathering in San Francisco, an event celebrating LGBTQ+ visibility during the World Cup and Pride Month.
The final chapter in the story of Dirt Alley was written Wednesday night as they unveiled the tiles of artwork on the pavement.
A Bay Area cancer patient is making more memories and living longer than his initial diagnosis thanks to a groundbreaking treatment for his particularly aggressive form of brain cancer.
The supervisor introduced the "Affordable Groceries Act," which includes two measures he hopes will get on the November ballot. One of the measures would tax large-chain grocery stores that have closed, yet are holding onto the property.
A local floral studio had the privilege of doing the floral arrangements for the "Love is You" gathering in San Francisco, an event celebrating LGBTQ+ visibility during the World Cup and Pride Month.
The Wings were 11 for 17 in the opening quarter and built a quick 26-17 lead before a cold second quarter.
A man arrested after a fire at a Berkeley animal shelter was charged with felony arson on Wednesday along with other charges, prosecutors said.
A Contra Costa County Sheriff's deputy has been arrested on multiple felony charges, the Sheriff's Office announced on Wednesday.
An interim police chief was appointed in San Leandro amid the investigation into Chief Angela Averiett, who has been charged in a 2025 hit-and-run collision.
Two weeks ago, Oakland Mayor Barbara Lee made a rare appearance before the City Council to promote a ballot initiative that would give her a lot more power over the operation of the city.
Emeryville police said the body found at a landfill facility in San Leandro has been identified as a man who was reported missing on June 1.
A Peninsula pastor is one of the first in the Bay Area to help provide a safe place for them while they search for housing in expensive Silicon Valley.
A woman died Monday after being stabbed in San Jose home and a man who knew her was arrested in connection with the killing, police said.
Richard Tillman, brother of the late National Football League star and U.S. Army Ranger Pat Tillman, was sentenced on Monday to five years in federal prison for setting a San Jose post office on fire in 2025.
Health officials in the San Francisco Bay Area issued a warning about a potential measles exposure after an infected resident traveled through San Francisco International Airport and local businesses.
San Jose police said a driver ran a red light and crashed into an uninvolved vehicle after refusing to pull over for Santa Clara officers. The driver who ran the red light was seriously injured, and his passenger was killed in the crash, police said.
Around 12:30 p.m., an officer patrolling near the Novato Fair shopping center spotted a man he believed was acting erratically and may be under the influence of drugs, police said.
A deer fawn was rescued on Wednesday from an outdoor wire dog crate at a Sonoma County home, authorities said.
A mountain biker who was injured in a remote Sonoma County trail Wednesday morning was airlifted to safety following a multi-agency rescue, authorities said.
The warning covers parts of the East Bay hills and the North Bay interior mountains, and begins at 11 p.m. Wednesday.
On Sunday, marchers began the second part of a three-day journey protesting U.S. Immigration and Customs Enforcement's presence in the Bay Area.
Major League Baseball has warned players about writing on their uniforms after San Francisco starter Landen Roupp and two other pitchers added Bible verses to their Pride Night caps on Friday night.
The Wings were 11 for 17 in the opening quarter and built a quick 26-17 lead before a cold second quarter.
Lionel Messi tied the Men's World Cup goals record with his first World Cup hat trick as Argentina topped Algeria.
For the first time since joining international competition, the Hashemite Kingdom of Jordan has qualified for the FIFA World Cup, marking a milestone achievement for the nation's soccer program and sparking celebrations among Jordanians around the world.
The family of former NFL star Aldon Smith is donating his brain to the Boston University CTE Center to research the long-term effects of repetitive brain injuries following his sudden death at age 36.
A man arrested after a fire at a Berkeley animal shelter was charged with felony arson on Wednesday along with other charges, prosecutors said.
A Contra Costa County Sheriff's deputy has been arrested on multiple felony charges, the Sheriff's Office announced on Wednesday.
An interim police chief was appointed in San Leandro amid the investigation into Chief Angela Averiett, who has been charged in a 2025 hit-and-run collision.
A woman died Monday after being stabbed in San Jose home and a man who knew her was arrested in connection with the killing, police said.
Richard Tillman, brother of the late National Football League star and U.S. Army Ranger Pat Tillman, was sentenced on Monday to five years in federal prison for setting a San Jose post office on fire in 2025.
U.K. Prime Minister Keir Starmer hopes to have a ban on kids using social media that is "designed to be addictive" enacted by early next year.
A woman has been found guilty of trespassing and other charges for her role in a protest outside the San Francisco headquarters of OpenAI last year, prosecutors said.
The iPhone was introduced in 2007, the same year the U.S. birth rate started to slide. The issues could be linked, a new analysis finds.
Meta pledged to invest $115 million to train electricians, plumbers and other workers needed to operate data centers.
SpaceX is setting aside a large chunk of shares for ordinary investors as it seeks to raise a record $75 billion. Here's what to know.
A Bay Area cancer patient is making more memories and living longer than his initial diagnosis thanks to a groundbreaking treatment for his particularly aggressive form of brain cancer.
Health officials in the San Francisco Bay Area issued a warning about a potential measles exposure after an infected resident traveled through San Francisco International Airport and local businesses.
Health officials in Berkeley said one person died and another person was hospitalized after contracting leptospirosis from rats that had infested their RV.
Grocery sales at two Target stores in San Jose were halted over the past week, after health inspectors found evidence of rodent infestations.
WHO chief Tedros Adhanom Ghebreyesus says risks from the Ebola outbreak in Congo and Uganda are "high at the national and regional levels, and low at the global level."
The supervisor introduced the "Affordable Groceries Act," which includes two measures he hopes will get on the November ballot. One of the measures would tax large-chain grocery stores that have closed, yet are holding onto the property.
Gov. Newsom's office is escalating its fight with the Trump administration, sending a letter Tuesday to Acting U.S. AG Todd Blanche accusing the Justice Department of conducting a politically motivated investigation into his wife and associates.
Two weeks ago, Oakland Mayor Barbara Lee made a rare appearance before the City Council to promote a ballot initiative that would give her a lot more power over the operation of the city.
Voters in the San Francisco Bay Area are deciding who will fill the remainder of former Rep. Eric Swalwell's congressional seat in a special primary election on Tuesday.
The FBI said it disrupted an attempt to attack Sunday's UFC America 250 event at the White House, with court records detailing an alleged plot to use small drones carrying explosives.
Major League Baseball has warned players about writing on their uniforms after San Francisco starter Landen Roupp and two other pitchers added Bible verses to their Pride Night caps on Friday night.
Many LGBTQ+ Pride events across the country have had to scale back or even cancel due to political and financial reasons. San Francisco was on the brink. Kara St. Cyr reports.
In one of the most competitive real estate markets in America, a San Francisco real estate agent dons fabulous drag to help promote homes for sale. Itay Hod reports.
The U.S. Department of Justice has launched an investigation into four California school districts over policies pertaining to the instruction of gender and sexual orientation.
Jason Collins, the NBA's first openly gay player, who went on to become a pioneer for inclusion and an ambassador for the league, has died, his family announced Tuesday.
Lionel Messi tied the Men's World Cup goals record with his first World Cup hat trick as Argentina topped Algeria.
Luke Skywalker's lightsaber from the "Star Wars" sequel "The Empire Strikes Back" is expected to sell for at least $1 million at an upcoming auction.
Rio de Janeiro's Military Fire Department said one of the helicopters crashed in the parking lot of a car dealership, where several electric vehicles were parked, igniting a fire.
With matches being played in 11 cities across the U.S., Mexico and Canada, fans are getting three World Cup opening ceremonies.
A gaming store in San Francisco keeps getting broken into, leading to loss after loss and a mountain of anxiety for the woman behind the business.
Ever since the COVID-19 pandemic, the Oakland Unified School District has seen an alarming spike in the number of unhoused students in the school system who deal with a host of challenges far beyond what most children face.
Meteorologist and CBS News Bay Area's resident pilot Lt. Jessica Burch got a treat during Fleet Week, taking to the skies with one of the Blue Angels.
A Bay Area man discovered his devastating loss left him with a new opportunity to rethink how he lives -- follow his journey in virtual reality, 360-degree video.
A groundbreaking medical study involving the UCSF Medical Center has shown some colorectal cancer patients can safely skip radiation treatment and enjoy a potentially higher quality of life.
Every day, San Francisco bar pilot Captain Zach Kellerman goes through what might just be the world's most dangerous commute.
Andrea Nakano reports on the makeover of a dirt alley that was mistakenly bought in an auction.
Anne Makovec reports on a Bay Area man who now has more time with his family after getting a specialized surgery.
Max Darrow reports on a floral studio that designed a floral arrangement for the “Love is You” gathering.
Sooji Nam reports on how a San Francisco supervisor is trying to address food deserts and grocery prices.
Community groups in Pajaro Valley in California's Central Coast say pesticides used near schools are contributing to higher rates of childhood cancer and are demanding change. Veronica Macias reports.
In 2025, KPIX is moving to a new community service award: the CBS News Bay Area Icon Award. Submit nominations for an outstanding community hero at kpix.com/icon.
It's the most wonderful time of the year for a South Bay woman who has played Mrs. Claus for more than 40 years for the children of North San Jose's Alviso District.
For residents of the Oakland Hills, the prospect of another wildfire always remains a concern. This week's Jefferson Awards winner has made it his mission to make the hills and other high-risk areas safer.
In East Palo Alto -- where state education numbers show more than nine in ten public school students are low income and more than half are English learners -- many are finding hope and connection at the Boys & Girls Clubs of the Peninsula.
This week's Jefferson Award winner is Army veteran who continues to live a life of service into his 80s, by feeding hundreds of San Francisco families a week.
A Bay Area man who overcame tremendous obstacles to excel in school has made it his mission to gear up other students for success in the classroom and in life.
For Students Rising Above scholar Josh Collins it took moving across the country to realize the value of his Bay Area family.
Samir Hooker had to grow up fast after his stepfather was shot dead 12 years ago. Now he is watching over his mom and sister while attending UC Berkeley.
It's hard enough to graduate from one of the most prestigious schools in the country when you're the first in your family to go to college. Imagine doing that while you're also trying to protect your parents from being deported?
Some students who are the first in their families to go to college face the challenge of balancing a rigorous academic load while still working to help support their family back home.