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If this week 15 matchup is anything like past confrontations between these two old AFL rivals, expect a hard-fought game in the trenches, with either Derek Carr or Philip Rivers pushing their respective teams to victory. Here are the key injuries that could impact the matchup.
The San Francisco 49ers face a daunting task this Sunday in Atlanta as they take on the high-scoring Falcons in the Georgia Dome. It's not likely the 49ers will snap their 12-game losing streak, especially without two starters on offense. Both wide receiver Torrey Smith and offensive lineman Joe Staley didn't practice this week, and the two players are listed as out and doubtful, respectively, for Week 15's game. Otherwise, the San Francisco roster looks relatively healthy for its matchup with the long-time NFC West Division foe from the East Coast.
The Oakland Raiders will likely have to wait at least another week to get defensive lineman Mario Edwards Jr. back on the field for the first time this season.
The Patriots and Broncos square off Sunday, pitting New England's pyrotechnic offense against Denver's granite defense.
Even as controversy swirls, Dak and the Cowboys will get the job done in Dallas while Matt Stafford and the Lions keep control of the NFC North with a win over Big Blue.
The year was 1983, and the San Francisco 49ers weren't the Team of the Decade just yet. In fact, after winning the Super Bowl for the first time in 1981, the 49ers slipped well back under .500 in the strike-shortened 1982 regular season and missed the playoffs. Thus, the following season was a big one for the San Francisco organization: Would the 49ers drift back into obscurity or would the team remain relevant in the NFC power hierarchy? One of the craziest games of 1983 was a road game in Atlanta against the Falcons, the 1980 and 1982 NFC West Division champions. Here's what happened.
The Raiders are among the NFL's surprise teams this season. The team sits at 10-3 heading into the home stretch. That said, the Raiders will need a perfect finish and help to win the AFC West crown.
Both the Rams and Seahawks look to turn things around on Thursday Night Football after blowout losses in Week 14.
NFL Commissioner Roger Goodell said it was good to meet face-to-face with Aldon Smith, but would not disclose any timetable for troubled former NFL star's return to the field with the Oakland Raiders.
Less than 24 hours after local officials approved a new $1.3 billion Oakland Raiders stadium plan, NFL Commissioner Roger Goodell told reporters covering the NFL owners meeting that there were "some real strength" with relocating to Las Vegas.
NFL Hall of Famer and CBS NFL Analyst, Dan Fouts, discusses three key AFC games with playoff implications in Week 15.
With the fate of the Oakland Raiders hanging in the balance, Alameda County officials voted 3-1 with one abstention to approve a deal for a new $1.3 billion stadium that supporters hope will keep the NFL team in town.
Running back Latavius Murray isn't concerned about the Oakland Raiders suffering through any type of hangover after their six-game winning streak ended last week in Kansas City.
Sitting at 5-8, the Chargers will look to play spoiler and make life miserable for the Raiders on the road in week 15.
Riding a 12-game losing streak isn't a good thing for the San Francisco 49ers as they prepare for a Week 15 matchup in Atlanta against the Falcons. Tied for first place in the NFC South Division and possessing the top scoring offense in the NFL, the Falcons present a daunting challenge for the 49ers right now.
The City of Oakland is getting ready to make what could be it's final play to keep the Raiders on Monday as city officials prepared to vote on the proposed stadium plan Tuesday.
Chip Kelly is facing the unenviable task of getting his team ready for its next game to stop the worst losing streak in franchise history.
The message on the banner being towed by a plane over the San Francisco 49ers Levi's Stadium summed up the frustrations of many fans over the team's dismal 1-12 record this season.
With a 17-3 halftime lead over the New York Jets, it looked as though the San Francisco 49ers were going to break an 11-game losing streak on Sunday at Levi's Stadium in Santa Clara. Alas, a team that has forgotten how to win fell apart in the second half, allowing the Jets to tie the score and eventually win on overtime.
Bilal Powell ran for 145 yards, including the game-ending 19-yard touchdown in overtime, to help Bryce Petty and the New York Jets rally from 14 points down to beat the San Francisco 49ers 23-17 in overtime on Sunday.
Hyde absolutely gashed the Jets from the outset of the game and at one point averaged 20.5 yards per carry.
Oakland and Alameda County leaders will vote Tuesday on a financial and development plan to build a $1.3 billion football stadium at the Coliseum site.
As the San Francisco 49ers approach a home game in Week 14 against the New York Jets this Sunday, the team is relatively healthy. That's good news for a team that is 1-11 and trying to avoid setting a franchise-worst mark for losses in a single season. The Jets matchup may be the last good chance for the 49ers to win another game in 2016.
The Kansas City Chiefs came away with a hard-fought 21-13 victory. In the process, Kansas City tied Oakland's record at 10-3. The Chiefs now lead the division since they won the head-to-head series.
The Buccaneers may be the NFL's most overlooked playoff contender, and not without reason. Can they change perceptions?
The company says its plan is misunderstood. They say they are offering new "edge computing" communications equipment which is more resilient during emergencies, a landing site for future aerial medical vehicles, and, yes, more parking.
On Saturday, the 250th anniversary of the event was commemorated on Pershing Square at the Presidio of San Francisco in a two-hour ceremony.
One man was killed and another was severely injured in a shooting in downtown San Jose on Sunday night, a block from what has been the site of FIFA World Cup festivities in the city.
Just before 2 p.m., the department said crews responded to a multi-story church at the intersection of California and Broderick for a one-alarm fire. The fire was then raised to two-alarm about 20 minutes later.
Two people were injured Monday after a small helicopter crashed in San Jose just outside of the Reid-Hillview County Airport.
The company says its plan is misunderstood. They say they are offering new "edge computing" communications equipment which is more resilient during emergencies, a landing site for future aerial medical vehicles, and, yes, more parking.
On Saturday, the 250th anniversary of the event was commemorated on Pershing Square at the Presidio of San Francisco in a two-hour ceremony.
One man was killed and another was severely injured in a shooting in downtown San Jose on Sunday night, a block from what has been the site of FIFA World Cup festivities in the city.
Just before 2 p.m., the department said crews responded to a multi-story church at the intersection of California and Broderick for a one-alarm fire. The fire was then raised to two-alarm about 20 minutes later.
Two people were injured Monday after a small helicopter crashed in San Jose just outside of the Reid-Hillview County Airport.
Just before 2 p.m., the department said crews responded to a multi-story church at the intersection of California and Broderick for a one-alarm fire. The fire was then raised to two-alarm about 20 minutes later.
The Archdiocese of San Francisco has agreed to pay nearly $400 million in a settlement with survivors of clergy sexual abuse, attorneys for the survivors announced on Monday.
The city of San Francisco is taking heightened police and security measures in advance of two major events in the Bay Area this week - the 4th of July and the knockout round of the FIFA World Cup.
On Sunday, volunteers were busy packing up many boxes of donations at Arepas Latin Cuisine in San Francisco for victims of the Venezuela earthquakes.
Two people were hospitalized and two suspects were arrested after a stabbing Sunday evening near the area of San Francisco's Civic Center, officials said.
A man was rescued with life-threatening injuries after an SUV went into the water at an Alameda boat launch Sunday night, firefighters said.
A three-alarm fire damaged two homes and an accessory dwelling unit Sunday afternoon in Castro Valley, displacing multiple people and pets, officials said.
The loss threatened the summer learning session, but on Sunday, the community stepped up at an impromptu fundraiser that raised spirits and funds.
Bore #2 on eastbound Highway 24 was temporarily closed beginning around noon and was reopened just after 1 p.m.
A woman faces multiple felony charges for allegedly setting a car on fire in Oakland and then attacking police officers and other first responders, the district attorney announced on Thursday.
One man was killed and another was severely injured in a shooting in downtown San Jose on Sunday night, a block from what has been the site of FIFA World Cup festivities in the city.
Two people were injured Monday after a small helicopter crashed in San Jose just outside of the Reid-Hillview County Airport.
One person was killed and another was critically injured in a shooting Sunday night in downtown San Jose, police said.
A brush fire burned close to homes in San Jose on Friday before firefighters stopped its forward progress.
California and Santa Clara County have filed motion for a preliminarty injunction against the Trump administrataion over what they claim is construction of a U.S. Immigration and Customs Enforcement facility near Gilroy.
The company says its plan is misunderstood. They say they are offering new "edge computing" communications equipment which is more resilient during emergencies, a landing site for future aerial medical vehicles, and, yes, more parking.
A wildfire was burning in a remote area in Napa County near the Lake County line on Monday and fire crews were using multiple aircraft to try and contain the fire.
A Bay Area tech entrepreneur is investing millions of dollars to preserve the character of Point Reyes Station to balance change, tourism, and preservation in the small Marin County town.
Frenchie's Owner Morgan Gray, a sommelier who has worked in the wine and hospitality industry for years, said downtown Santa Rosa offered the right mix of affordability and character for her first small business.
A former officer for the California Department of Corrections and Rehabilitation was convicted of child sex crimes in Napa involving three family members after an eight-day trial, prosecutors announced Thursday.
Robbie Ray outpitched Chris Sale in a matchup of Cy Young Award winners and the San Francisco Giants held off the Atlanta Braves for a 3-2 victory.
Rafael Devers homered twice and drove in four runs as the San Francisco Giants beat the Atlanta Braves 5-0 behind Logan Webb's magnificent pitching.
Mauricio Dubón had two hits and scored twice against his former team, Ozzie Albies drove in two runs and the Atlanta Braves beat the San Francisco Giants 3-1 to stop a four-game skid.
In a game where the results didn't really matter, USA fans had a lot of spirit for the final match in the World Cup's group stage. But at a watch party at Pier 39, fans quickly realized they needed more than spirit to carry them through the game.
Jonah Heim's RBI single tied the game, Lawrence Butler followed with a go-ahead RBI hit and the Athletics scored four times with two out in the ninth inning Thursday, rallying for a 9-6 win over the San Francisco Giants.
One man was killed and another was severely injured in a shooting in downtown San Jose on Sunday night, a block from what has been the site of FIFA World Cup festivities in the city.
One person was killed and another was critically injured in a shooting Sunday night in downtown San Jose, police said.
A suspect was arrested Saturday after a shooting near San Francisco's Pride celebrations left one person wounded and an officer hurt during a foot chase, police said.
A woman faces multiple felony charges for allegedly setting a car on fire in Oakland and then attacking police officers and other first responders, the district attorney announced on Thursday.
The shooting happened around 3 p.m. on the 550 block of 17th Street.
The company says its plan is misunderstood. They say they are offering new "edge computing" communications equipment which is more resilient during emergencies, a landing site for future aerial medical vehicles, and, yes, more parking.
The heaviest demand on America's water supply isn't data centers or AI. It's from everyday uses such as growing food, watering lawns and flushing toilets.
The most advanced artificial intelligence models are improving quickly enough to outsmart prevailing cybersecurity know-how within months, the Five Eyes spy agency alliance is warning.
The recall follows multiple incidents in which Waymo robotaxis drove past ramp-closure signs and into freeway construction zones.
U.K. Prime Minister Keir Starmer hopes to have a ban on kids using social media that is "designed to be addictive" enacted by early next year.
A Bay Area cancer patient is making more memories and living longer than his initial diagnosis thanks to a groundbreaking treatment for his particularly aggressive form of brain cancer.
Health officials in the San Francisco Bay Area issued a warning about a potential measles exposure after an infected resident traveled through San Francisco International Airport and local businesses.
Health officials in Berkeley said one person died and another person was hospitalized after contracting leptospirosis from rats that had infested their RV.
Grocery sales at two Target stores in San Jose were halted over the past week, after health inspectors found evidence of rodent infestations.
WHO chief Tedros Adhanom Ghebreyesus says risks from the Ebola outbreak in Congo and Uganda are "high at the national and regional levels, and low at the global level."
The Supreme Court on Monday ruled that states can count mail ballots that are cast by Election Day but arrive later, rejecting a GOP challenge to a Mississippi law.
A unanimous federal jury found that a preponderance of evidence supported Carroll's claim that Mr. Trump sexually abused her.
Americans weighed in on what's best about the U.S., its greatest invention, most representative food and more in latest CBS News poll.
The U.S. military says it hit Iranian targets over Iran's drone attack on a commercial vessel in the Strait of Hormuz, marking the first American strikes on Iran since the two countries formally agreed to extend a ceasefire last week.
As California Gov. Gavin Newsom eyes a 2028 presidential bid, he's calling for a national tax on billionaires and a public stake in AI, though he opposes a state ballot measure to tax billionaires.
LGBTQ+ communities have significantly higher rates of unemployment than the general population. Kelsi Thorud reports on how the City of Oakland is empowering LGBTQ+ job seekers during Pride Month.
The fallout over the opposition by a handful of San Francisco Giants players against the team's Pride Night celebrations has prompted an investigation of Major League Baseball by the Trump administration.
Major League Baseball has warned players about writing on their uniforms after San Francisco starter Landen Roupp and two other pitchers added Bible verses to their Pride Night caps on Friday night.
Many LGBTQ+ Pride events across the country have had to scale back or even cancel due to political and financial reasons. San Francisco was on the brink. Kara St. Cyr reports.
In one of the most competitive real estate markets in America, a San Francisco real estate agent dons fabulous drag to help promote homes for sale. Itay Hod reports.
The two-hour special will have live reporting from the San Francisco Pride Parade route and stories featuring people from the Bay Area's LGBTQ community.
Clive Davis helped shape the careers of music stars including Janis Joplin, Bruce Springsteen and Whitney Houston.
Record producer Tay Keith was found dead in his Nashville home by officers performing a welfare check, police said.
Lionel Messi tied the Men's World Cup goals record with his first World Cup hat trick as Argentina topped Algeria.
Luke Skywalker's lightsaber from the "Star Wars" sequel "The Empire Strikes Back" is expected to sell for at least $1 million at an upcoming auction.
Ever since the COVID-19 pandemic, the Oakland Unified School District has seen an alarming spike in the number of unhoused students in the school system who deal with a host of challenges far beyond what most children face.
Meteorologist and CBS News Bay Area's resident pilot Lt. Jessica Burch got a treat during Fleet Week, taking to the skies with one of the Blue Angels.
A Bay Area man discovered his devastating loss left him with a new opportunity to rethink how he lives -- follow his journey in virtual reality, 360-degree video.
A groundbreaking medical study involving the UCSF Medical Center has shown some colorectal cancer patients can safely skip radiation treatment and enjoy a potentially higher quality of life.
Every day, San Francisco bar pilot Captain Zach Kellerman goes through what might just be the world's most dangerous commute.
Kevin Ko reports on a three-alarm fire at a church in San Francisco.
Kara St. Cyr reports on the egg market.
Soccer fans gathered outside the San Jose Mariott in Downtown San Jose on Monday to welcome of the U.S. men's national team for their Round of 32 match Wednesday against Bosnia and Herzegovina at Levi's Stadium in Santa Clara.
Brad Hamilton reports on safety plans for two big celebrations in the Bay Area.
Direct descendants of the Spanish expedition that established the first reliable overland route from Mexico to what is now modern-day San Francisco. John Ramos reports.
In 2025, KPIX is moving to a new community service award: the CBS News Bay Area Icon Award. Submit nominations for an outstanding community hero at kpix.com/icon.
It's the most wonderful time of the year for a South Bay woman who has played Mrs. Claus for more than 40 years for the children of North San Jose's Alviso District.
For residents of the Oakland Hills, the prospect of another wildfire always remains a concern. This week's Jefferson Awards winner has made it his mission to make the hills and other high-risk areas safer.
In East Palo Alto -- where state education numbers show more than nine in ten public school students are low income and more than half are English learners -- many are finding hope and connection at the Boys & Girls Clubs of the Peninsula.
This week's Jefferson Award winner is Army veteran who continues to live a life of service into his 80s, by feeding hundreds of San Francisco families a week.
A Bay Area man who overcame tremendous obstacles to excel in school has made it his mission to gear up other students for success in the classroom and in life.
For Students Rising Above scholar Josh Collins it took moving across the country to realize the value of his Bay Area family.
Samir Hooker had to grow up fast after his stepfather was shot dead 12 years ago. Now he is watching over his mom and sister while attending UC Berkeley.
It's hard enough to graduate from one of the most prestigious schools in the country when you're the first in your family to go to college. Imagine doing that while you're also trying to protect your parents from being deported?
Some students who are the first in their families to go to college face the challenge of balancing a rigorous academic load while still working to help support their family back home.