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Jimmy Garoppolo made it through the week of practice completely healthy and will start at quarterback Sunday for San Francisco but the 49ers could be missing left tackle Trent Williams.
The Las Vegas Raiders were determined not to let Jon Gruden's undoing lead to their own downfall.
Derek Carr sliced up the Denver defense for 341 yards and two touchdowns, Maxx Crosby made three sacks and the Las Vegas Raiders started the post-Jon Gruden era with a 34-24 thrashing of the bewildered Broncos on Sunday.
When Jon Gruden returned to the then-Oakland Raiders back in 2018 he was greeted with a pep rally news conference, owner Mark Davis calling it a "dream come true" and the "biggest day of his life."
Rookie Trey Lance's first career start for the San Francisco 49ers featured a bad interception, a couple of promising moments and a knee injury that could sideline him for a week or two.
The Arizona Cardinals rode a stellar defensive performance to a 17-10 win over the San Francisco 49ers on Sunday.
Justin Fields threw his first career touchdown pass and the Chicago Bears' defense largely shut down the Las Vegas Raiders' high-powered offense in a 20-9 victory Sunday.
The San Francisco 49ers placed star tight end George Kittle on injured reserve Saturday with a calf injury that has been bothering him for weeks.
Rookie quarterback Trey Lance will make his first start for the San Francisco 49ers after Jimmy Garoppolo was ruled out of this week's game with a calf injury.
Now in his third season with the 49ers, Deebo Samuel is leading the NFL in yards receiving through four weeks.
San Francisco 49ers coach Kyle Shanahan was still holding onto hope Wednesday that injured quarterback Jimmy Garoppolo can recover enough to be able to play Sunday against the NFC West leading Phoenix Cardinals.
The Seattle Seahawks rebounded from back-to-back losses by beating the San Francisco 49ers 28-21 on Sunday.
The San Francisco 49ers could be down two more starting cornerbacks for Sunday's game against Seattle but are holding out hope star tight end George Kittle can play.
After watching his offense sputter for most of the first half the past two weeks, coach Kyle Shanahan said Wednesday that getting rookie Trey Lance in for more plays in place of starter Jimmy Garoppolo won't help change that.
It was an emotional rollercoaster for the thousands of San Francisco 49ers fans who flocked to Levi's Stadium for the team's first home opener with fans since 2019. There was a wild swing in the game's final minute.
Aaron Rodgers completed two deep passes to Davante Adams on a last-minute drive, setting set up Mason Crosby's 51-yard field goal on the final play of the game that gave the Green Bay Packers a 30-28 victory over the San Francisco 49ers.
The Las Vegas Raiders have won their second overtime game in three weeks to improve to 3-0, the first time the franchise has begun a season that well since 2002.
Staying on the road between East Coast games has been a successful formula for the San Francisco 49ers under coach Kyle Shanahan.
Derek Carr threw for 382 yards and two touchdowns, including a pretty 61-yard strike to Henry Ruggs midway through the fourth quarter, as the Las Vegas Raiders toppled Pittsburgh 26-17 on Sunday.
The AFC East goes to battle in week 2, as all four teams compete against each other, with the Jets hosting the Patriots and the Bills visiting the Dolphins.
Raheem Mostert, the lead running back for the San Francisco 49ers, announced on social media Tuesday that he planned to undergo season-ending knee surgery.
The 49ers led 38-10 early in the fourth quarter and allowed Detroit to score 23 points in three-plus minutes to pull within eight points, barely holding on for a 41-33 win over the Lions on Sunday.
Rookie quarterback Trey Lance made it through a week of practice with no setbacks to his injured right index finger and is cleared to play in the San Francisco 49ers' season-opener at Detroit.
The conversation outside the walls of the San Francisco 49ers training camp has come to an end, veteran Jimmy Garoppolo will start at quarterback for the team opener against Detroit on Sunday.
Questions remain about the San Francisco 49ers' rookie quarterback Trey Lance, who came to practice Monday without a splint on his finger, showing signs of progress from a recent injury. Yet he still didn't throw a ball.
