The popular show will play at Wynn Las Vegas, joining "Le Reve," a watery, acrobatic production by Cirque du Soleil's former creative director, and the Tony-winning "Avenue Q" that opens Aug. 27.
"It's the most intense concentration of entertainment on the Las Vegas Strip," Wynn told The Associated Press. "I'm not sure that we're done yet."
Wynn said he'll build a 1,600-seat theater, one of three that was planned for the $2.7 billion megaresort. Wynn will pay for the venue and staging of the show at a cost of more than $50 million.
"We made a deal very like much like we always do," Wynn said. "We'll build a theater and you bring a show and we'll share in the profits."
The agreement calls for "Spamalot" to play at Wynn Las Vegas for 10 years if the hotel-casino picks up a three-year renewal option. The cast hasn't been determined but the show is slated to open in 2007.
The Las Vegas production will span 90 minutes, compared with the approximate two-hour version in New York City, which won three 2005 Tony Awards, including Best Musical.
"Spamalot" will be performed 12 times a week, with ticket prices from $80 to $100, Wynn said. Wynn says he'll also add a retail component and restaurant to complement the show.