Updated 6:20 p.m. ET
New York - One positive report on the economy was not enough to make investors more confident.
The stock market ended mixed Friday after a day of muddled trading. Among the three main U.S. stock indexes, one edged higher, one closed little changed and the other closed lower.
Investors focused on the tensions in Ukraine, where the region of Crimea was preparing for a referendum on whether to split away and become part of Russia. It was enough of a reason to sell into the weekend and offset optimism over a pickup in hiring by U.S. employers last month. Early Friday, the Labor Department said the economy added 175,000 jobs in February, which easily topped economists' forecasts.
While encouraging, investors didn't see the February jobs report as part of a broader trend. December and January figures were mediocre, and the harsh winter weather has closed factories, cut into auto sales and caused existing-home sales to plummet for the last three months.
"People are hoping and praying that the recent slowness was weather-related, and while this report gave people a little bit of hope that is the case, it is still too early to tell," said Krishna Memani, chief investment officer of OppenheimerFunds.
The Standard & Poor's 500 index closed roughly flat, up a point, or 0.05 percent, to 1,878.04. The Dow Jones rose 30.83 points, or 0.2 percent, to 16,452.72 and the Nasdaq composite lost 15.90 points, or 0.4 percent, to 4,336.22.
On the whole, the overall tone of the market was slightly negative. Three stocks fell for every two that rose on the New York Stock Exchange. Of the 10 industry sectors in the S&P 500 index, six fell.
Biotechnology and health care stocks were among the biggest decliners. Biogen Idec fell roughly 4 percent, and Amgen fell 2 percent. The Nasdaq composite index is more heavily weighted to biotechnology and specialty pharmaceutical companies, which is part of the reason the index fell even though the Dow and S&P 500 rose.
Bond prices fell following the release of the jobs numbers. The yield on the 10-year U.S. Treasury note rose to 2.79 percent, up from 2.74 percent on Thursday. Gold fell $13.60, or 1 percent, to $1,338.20.
As they have for much of the week, investors turned their attention overseas.
Lawmakers in Russian-occupied Crimea unanimously declared they wanted to join Russia and would put the decision to voters in 10 days. President Barack Obama and several other Western leaders have condemned the referendum.
Ukraine's economy is not large enough to cause serious damage to the global economy. But the geopolitical tensions that Russia's occupation is creating between Russia, Europe, Ukraine and the U.S. could potentially be destabilizing for the region, investors say. In particular, trade between Europe and Russia could be severely impacted.
Germany's DAX index fell 2 percent Friday and is down nearly 4 percent this week. The Euro Stoxx 50 index, the European equivalent of the Dow Jones industrial average, fell 1.7 percent this week.
"Europe has a lot more to lose in these Russia-Ukraine tensions than the U.S.," said Andres Garcia-Amaya, a global markets strategist with J.P. Morgan Assets Management.
The geopolitical tensions could flare up at any point, Garcia-Amaya said, giving investors fewer reasons to hold positions through the weekend.
In other company news:
-- The discount retail chain Big Lots soared $6.72, or 23 percent, to $35.97. Big Lots reported a decline in fourth-quarter profits but the company's sales came in much better than expected. The company also said it would shut down its struggling Canadian operations.
-- Grocery store chain Safeway fell 87 cents, or 2 percent, to 38.60 after it said private equity firm Cerberus Capital would buy the company for $9 billion.