In the U.S., sales at restaurants open at least 13 months climbed 5.7 percent - its biggest monthly increase since it recorded a 6.1 percent gain in April 2009.
Overall, the measure rose 7 percent around the globe. It climbed 5.3 percent in Europe and 10.1 percent in the rest of the world, the world's largest hamburger chain said in a statement on Monday.
The figure is considered an important gauge of a restaurant chain's performance because it excludes the effects of restaurants that open or close during the year.
McDonald's shares climbed $1.21 to $72.95 in early trading Monday. The company's stock closed Friday at $71.74.
McDonald's is based in the Chicago suburb of Oak Brook, Ill. It has more than 32,000 restaurants around the world in 100 countries. About 14,000 of its locations are in the U.S.