"I am gay, George," the unidentified man said during a news conference at the Venice Film Festival Tuesday. "Take me, choose me George, please. May I kiss you, just once?"
Clooney was unflappable in responding with a smile, "It's hard when you take a big chance and it doesn't really work."
Clooney was attending the Venice Film Festival to present his new movie "The Men Who Stare at Goats," directed by Grant Heslov. The film was screened Tuesday out of competition.
The actor arrived in Venice with Italian actress Elisabetta Canalis.