A spokeswoman at Providence Alaska Medical Center, where the four survivors were taken, says O'Keefe's condition has improved from critical to serious.
O'Keefe's son, Kevin, remains in fair condition. Jim Morhard also is in fair condition, and William "Willy" Phillips Jr. is in good condition.
The group was flying to a fishing camp Monday when their plane crashed.
The Alaska Department of Health and Social Services said Friday that all five people who were killed died from blunt-force injuries.
State medical examiner Katherine Raven tells The Anchorage Daily News the blunt-force trauma injuries weren't survivable and that the victims likely died soon after impact.