Angela A. Blackwell of Saginaw Township is charged with first-degree criminal sexual conduct and pandering.
She remained in jail Wednesday pending a preliminary hearing set for March 30. Her lawyer did not immediately return a phone call seeking comment.
Police are searching for Johnnie L. Griffin on first- and second-degree criminal sexual conduct and firearms charges.
If convicted, the pair could be sentenced to at least 25 years in prison.
Detective Sgt. Joseph Dutoi tells The Saginaw News that Griffin had sex with the girl between September and February, while she was in Blackwell's care.