After seven scoreless innings, Jermaine Dye singled home the only run in the eighth, and the White Sox beat the Houston Astros 1-0 Wednesday night to win their first title in 88 years.
Just a year ago, the same story line captivated baseball when the long-suffering Boston Red Sox swept St. Louis to capture their first title in 86 seasons.
Who's next, the Chicago Cubs, without a championship since 1908?
"It's unbelievable, unbelievable," catcher A.J. Pierzynski said.
It was a perfect end to an unforgettable season, reports CBS News correspondent Steve Futterman, as the White Sox made a clean sweep of the hard-fought series by winning the first four games, two of them by one run, and two by two runs.
It was the third title for the White Sox, following wins in 1906 and 1917. And it was the first since "Shoeless" Joe Jackson and the "Black Sox" threw the 1919 Series against Cincinnati.
In the Windy City, where the Cubs have long been king, Chicago's South Side team for once trumped its North Side rival, no small feat for the Sox, and the city, or at least the "South Side" of the city, erupted in celebration, reports CBS News correspondent Cynthia Bowers.
"It's like Christmas, when you haven't experienced Christmas in 70, 80 years," said jubilant Chicago fan Joaquin Otto.
Fans kissed, hugged, chanted, sang, danced on tables and hoisted brooms symbolizing the sweep in Chicago bars after the Sox won, reports Bob Roberts of CBS radio station WBBM-AM.
Owner Jerry Reinsdorf once said he'd trade all six of the Chicago Bulls' NBA titles for a single Series ring. No swap is needed now: He's got the prize he dreamed of since he was a kid growing up in Brooklyn.
"I hope this is not a dream," he said, holding the trophy under his left arm like a kid clutching his first baseball glove.
White Sox manager Ozzie Guillen said during the regular season that he might retire if his team went on to win the Series, and now he'll have to reveal that decision. He hinted after the game that he wanted a new contract.
"Now I'm going to make my money," he said playfully, looking at Reinsdorf.