Updated at 10:41 p.m.
Bullock, wearing a glittery black dress, received a standing ovation as she accepted the MTV Generation Award in her first live televised appearance since she split with unfaithful husband Jesse James earlier this year. The 45-year-old actress used her acceptance speech to clear up tabloid rumors - "No. 1: I'm not dead." - and smooch Scarlett Johansson.
"Now that we have done that, can we please go back to normal?" said a smiling Bullock.
Kristen Stewart won the first golden popcorn trophy handed out at the fan-favorite MTV award show, hosted by "Parks and Recreation" funnyman Aziz Ansari. Stewart was honored for best female performance for her role as Bella Swan in "The Twilight Saga: New Moon" at Sunday's over-the-top and often-bleeped ceremony at the Gibson Amphitheatre.
"I guess 'Twilight' is really awesome, and I agree," said a fidgety Stewart. "Woo!"
Stewart and her "Twilight" co-star Robert Pattinson also landed the best kiss award for the second consecutive year. Other winners included "Obsessed" co-stars Beyonce Knowles and Ali Larter for best fight, "Jennifer's Body" star Amanda Seyfried for the first-ever "scared-as-s--t moment" and "Up in the Air" co-star Anna Kendrick for breakout star.
"This is the coolest moment ever," said Kendrick, clutching her popcorn trophy. "This is going on my coffee table."
Tom Cruise launched the show as his "Tropic Thunder" character Les Grossman, a profanity-spewing Hollywood producer. In the opening bit, Grossman used Michael Cera as a human bookend and berated "The Karate Kid" star Jaden Smith as his father Will Smith looked on. He later appeared on stage and danced alongside pop star Jennifer Lopez to Ludacris' "Get Back."