The channel also features clips of others, including her late father Otto and Nelson Mandela, talking about Anne, museum spokeswoman Annemarie Bekker said Friday.
"It is really a great platform to show all the different kinds of films and documentaries about Anne Frank," Bekker added.
The channel shows footage taken during a neighbor's wedding on July 22, 1941. It briefly shows Anne before she and her family were forced into hiding to avoid the Nazis during their World War II occupation of the Netherlands.
The fleeting moving images of Anne already are on display at the museum and on its Web site in slightly shorter versions.
Bekker said the YouTube channel also has a video about the making of a 3-D virtual version of the secret annex concealed in an Amsterdam canalside house where the Frank family hid for 25 months until they were betrayed and deported.
The virtual version of the secret annex is due to be formally launched next year to help mark the 50th anniversary of the museum's founding.
Anne died aged 15 of typhus in the German concentration camp of Bergen-Belsen, seven months after her arrest and just two weeks before British and Canadian troops liberated the camp. Her posthumously published diary has made her a symbol of all Jews killed in World War II.
Watch the video here: