Injured Jimmy Garoppolo Out For Sunday; Rookie Trey Lance Gets 1st Start Vs. Cardinals
Rookie quarterback Trey Lance will make his first start for the San Francisco 49ers after Jimmy Garoppolo was ruled out of this week's game with a calf injury.
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Rookie quarterback Trey Lance will make his first start for the San Francisco 49ers after Jimmy Garoppolo was ruled out of this week's game with a calf injury.
Now in his third season with the 49ers, Deebo Samuel is leading the NFL in yards receiving through four weeks.
San Francisco 49ers coach Kyle Shanahan was still holding onto hope Wednesday that injured quarterback Jimmy Garoppolo can recover enough to be able to play Sunday against the NFC West leading Phoenix Cardinals.
The Seattle Seahawks rebounded from back-to-back losses by beating the San Francisco 49ers 28-21 on Sunday.
The San Francisco 49ers could be down two more starting cornerbacks for Sunday's game against Seattle but are holding out hope star tight end George Kittle can play.
After watching his offense sputter for most of the first half the past two weeks, coach Kyle Shanahan said Wednesday that getting rookie Trey Lance in for more plays in place of starter Jimmy Garoppolo won't help change that.
Aaron Rodgers completed two deep passes to Davante Adams on a last-minute drive, setting set up Mason Crosby's 51-yard field goal on the final play of the game that gave the Green Bay Packers a 30-28 victory over the San Francisco 49ers.
Staying on the road between East Coast games has been a successful formula for the San Francisco 49ers under coach Kyle Shanahan.
Jimmy Garoppolo threw one touchdown pass and ran in for a score, leading the San Francisco 49ers to a 17-11 victory over the Philadelphia Eagles on Sunday.
Raheem Mostert, the lead running back for the San Francisco 49ers, announced on social media Tuesday that he planned to undergo season-ending knee surgery.
Parys Haralson, a former linebacker for the San Francisco 49ers and New Orleans Saints, has died. He was 37.
Following a 2020 season that saw an NFL-record number of injuries, the San Francisco 49ers began the 2021 regular season with more serious injuries to key players Jason Verrett and Raheem Mostert.
The 49ers led 38-10 early in the fourth quarter and allowed Detroit to score 23 points in three-plus minutes to pull within eight points, barely holding on for a 41-33 win over the Lions on Sunday.
Rookie quarterback Trey Lance made it through a week of practice with no setbacks to his injured right index finger and is cleared to play in the San Francisco 49ers' season-opener at Detroit.
The conversation outside the walls of the San Francisco 49ers training camp has come to an end, veteran Jimmy Garoppolo will start at quarterback for the team opener against Detroit on Sunday.
Mike Evans, Demarcus Robinson and Deebo Samuel caught touchdown passes from Brock Purdy, and the San Francisco 49ers routed the Los Angeles Rams 27-7 in the first NFL regular-season game in Australia.
The longest road trip in NFL history has brought the San Francisco 49ers and the Los Angeles Rams to Australia's sports capital for a season opener in front of more than 100,000 football-hungry fans packed into the Southern Hemisphere's largest stadium.
Shay Whitcomb's RBI double capped a six-run rally with two out in the eighth inning as the San Francisco Giants beat the St. Louis Cardinals 7-6 on Wednesday to complete a series sweep.
San Francisco 49ers coach Kyle Shanahan says defensive tackle Alfred Collins is out for the season after tearing his patellar tendon.
Bryce Eldridge hit a solo home run in the first inning and extended his on-base streak to 17 games, Christian Koss connected the next inning, and the San Francisco Giants beat the St. Louis Cardinals 2-1.
Aaron Donald won't play Week 1, delaying his return to the field after ending his retirement last month.
San Francisco 49ers star pass rusher Nick Bosa is set to play in the season opener against the Los Angeles Rams in his first game action since a tearing a knee ligament last September.
Shay Whitcomb chopped a single with one out in the 11th inning for his first career game-ending RBI, and the San Francisco Giants beat the St. Louis Cardinals 5-4.
Bo Bichette launched a go-ahead three-run homer with two outs in the eighth inning after an intentional walk to Juan Soto, and the Mets rallied for a 4-2 victory over the Giants on Sunday.
A man who was arrested after a massive fire at a condominium complex on the Peninsula last month will not be charged, prosecutors said.
A vegetation fire that broke out in Mendocino County on Thursday has burned more than 1,000 acres and has prompted evacuations, officials said.
Amid rising rents and evictions, San Francisco Mayor Daniel Lurie declared a rent emergency Thursday, proposing several tenant protection measures. But many say there is more work to do.
PG&E says about 14,000 customers across 11 Northern California counties could lose power this weekend as gusty winds and dry conditions raise wildfire concerns.
A mistrial was declared in the murder trial of Lindsay Clancy after jurors could not reach a unanimous decision. One of the jurors shares details on their deliberations in an interview with Gayle King.
A man who was arrested after a massive fire at a condominium complex on the Peninsula last month will not be charged, prosecutors said.
Amid rising rents and evictions, San Francisco Mayor Daniel Lurie declared a rent emergency Thursday, proposing several tenant protection measures. But many say there is more work to do.
Less than 10% of plastic ever gets recycled. The rest ends up in landfills, where it eventually breaks down into microplastics that get into the air, soil, and water.
They're loud, playful and one of San Francisco's most recognizable icons. But this summer, sea lions along the Central California coast are also signaling a troubling change in the ocean.
With less than two months to go, supporters and critics of a regional tax measure continue to campaign before voters head to the polls in November.
At least 18 businesses in Pleasanton were burglarized early Thursday morning in a smash-and-grab spree that primarily targeted restaurants, according to police.
A driver accused of fleeing from Alameda County sheriff's deputies ended up driving the wrong way on Interstate 580, crashing into another vehicle and triggering a temporary freeway shutdown before the driver and passenger were arrested, officials said.
BART announced that Green Line service between Berryessa and Daly City has been suspended as crews make repairs after equipment issues and a substation fire led to delays.
An East Bay man has been charged for allegedly engaging in human trafficking that victimized women and minors in multiple states, prosecutors said.
The Pittsburg Police Department on Tuesday acknowledged the security lapses that led to a shooting inside the department's booking area that injured an officer and a suspect.
Perched on a cliff overlooking the Pacific, Nepenthe has been a fixture along Big Sur's Highway 1 for more than seven decades.
A San Francisco Bay Area woman who is accused of intentionally running over her friend with her vehicle has been charged in connection with a deadly stabbing of another person she knew, authorities said.
Residents of a duplex are safe after a fire broke out in a San Jose neighborhood early Thursday morning.
A passenger in a vehicle that was stopped by police in Santa Clara over the weekend died after suffering a medical emergency during the stop, police said.
Authorities on California's Central Coast said they have located a car linked to an Amber Alert involving a missing teen sexual assault victim but have yet to find the girl and her father, who allegedly impregnated her.
A vegetation fire that broke out in Mendocino County on Thursday has burned more than 1,000 acres and has prompted evacuations, officials said.
A vegetation fire broke out in Napa County near Lake Berryessa on Wednesday, prompting an evacuation warning that was later lifted.
The National Park Service is looking for a residential volunteer to help staff the historic Point Reyes Lighthouse this fall and winter, with free housing included.
A minor earthquake shook Sonoma County Thursday morning, according to the U.S. Geological Survey.
Suisun City and the California Forever development group announced on Tuesday that they have finalized the first phase of a revitalization plan for the downtown area of the city.
Mike Evans, Demarcus Robinson and Deebo Samuel caught touchdown passes from Brock Purdy, and the San Francisco 49ers routed the Los Angeles Rams 27-7 in the first NFL regular-season game in Australia.
The longest road trip in NFL history has brought the San Francisco 49ers and the Los Angeles Rams to Australia's sports capital for a season opener in front of more than 100,000 football-hungry fans packed into the Southern Hemisphere's largest stadium.
Shay Whitcomb's RBI double capped a six-run rally with two out in the eighth inning as the San Francisco Giants beat the St. Louis Cardinals 7-6 on Wednesday to complete a series sweep.
San Francisco 49ers coach Kyle Shanahan says defensive tackle Alfred Collins is out for the season after tearing his patellar tendon.
Bryce Eldridge hit a solo home run in the first inning and extended his on-base streak to 17 games, Christian Koss connected the next inning, and the San Francisco Giants beat the St. Louis Cardinals 2-1.
A man who was arrested after a massive fire at a condominium complex on the Peninsula last month will not be charged, prosecutors said.
The trial of Khalid Sheikh Mohammed and three other alleged 9/11 plotters is scheduled to begin in June 2028.
A driver accused of fleeing from Alameda County sheriff's deputies ended up driving the wrong way on Interstate 580, crashing into another vehicle and triggering a temporary freeway shutdown before the driver and passenger were arrested, officials said.
A San Francisco Bay Area woman who is accused of intentionally running over her friend with her vehicle has been charged in connection with a deadly stabbing of another person she knew, authorities said.
Residents of a duplex are safe after a fire broke out in a San Jose neighborhood early Thursday morning.
The development of AI "doesn't look that different from say, 'Terminator,' or from science fiction films," Jacob Coxon said.
"What happens inside frontier AI companies now clearly affects everyone outside of them," an expert said following the hack on Hugging Face by AI agents being tested by OpenAI.
Anthropic announced a fourth cybersecurity incident in which Claude gained access to the open internet during testing.
Apple introduced the iPhone 18 at its annual tech showcase and unveiled its first foldable phone.
A top Anthropic researcher says there's more than a 10% chance AI "could kill all humans," after a colleague resigned over similar concerns.
Officials in the East Bay city of Berkeley have issued a warning to residents and doctors amid a rising number of bats that have tested positive for rabies.
Patients taking the first-of-a-kind pill, called daraxonrasib, lived for a median of 13.2 months compared with 6.7 months for chemotherapy recipients, studies showed.
Moderna and Merck announced study results that reflect a "landmark moment" in treatment for one of the deadliest forms of skin cancer.
Multiple unpermitted street food vendors in Fairfield were cited for violations last week after inspections found them selling food unsafe for public consumption, authorities said.
After weeks of uncertainty, students at Richmond's John F. Kennedy High School will start their classes on schedule after weeks after toxic chemicals were found underneath the campus.
Amid rising rents and evictions, San Francisco Mayor Daniel Lurie declared a rent emergency Thursday, proposing several tenant protection measures. But many say there is more work to do.
The trial of Khalid Sheikh Mohammed and three other alleged 9/11 plotters is scheduled to begin in June 2028.
Four former presidents are at the World Trade Center memorial site for 9/11 commemorations, while President Trump spoke at the Pentagon.
The White House has not publicly released the voluntary framework for testing frontier AI models that it finalized in August.
President Trump pledged $5,000 to all American adults if Republicans retain control of Congress. You may not be able to take that to the bank.
California Attorney General Rob Bonta has joined a coalition of 19 attorneys general in supporting a federal lawsuit challenging Idaho's law that bars transgender students from using school restrooms and other sex-separated facilities that align with their gender identity.
Berlin police did not identify the suspect, who is still at large, by name but said that he was already known to police and is from Berlin.
LGBTQ+ communities have significantly higher rates of unemployment than the general population. Kelsi Thorud reports on how the City of Oakland is empowering LGBTQ+ job seekers during Pride Month.
The fallout over the opposition by a handful of San Francisco Giants players against the team's Pride Night celebrations has prompted an investigation of Major League Baseball by the Trump administration.
Major League Baseball has warned players about writing on their uniforms after San Francisco starter Landen Roupp and two other pitchers added Bible verses to their Pride Night caps on Friday night.
Dolly Parton died in Nashville on Aug. 25 at the age of 80 — a shock to fans around the world who weren't aware of her illness.
A special exhibition honoring the legacy of the Grateful Dead opens in San Francisco's Golden Gate Park, which will include one of the most recognized symbols of the counterculture era of the early 60s.
While performing in St. Louis on Saturday night, Lionel Richie appeared at one point to lean on a piano for support, according to video from the show.
Fans of some of Hollywood's most iconic movies lined up outside legendary filmmaker Phil Tippett's Berkeley studio Friday, hoping to take home a piece of movie history.
Pokémon fans from across the country and around the world are pouring into San Francisco this weekend for the largest Pokémon World Championships in the event's history.
Ever since the COVID-19 pandemic, the Oakland Unified School District has seen an alarming spike in the number of unhoused students in the school system who deal with a host of challenges far beyond what most children face.
Meteorologist and CBS News Bay Area's resident pilot Lt. Jessica Burch got a treat during Fleet Week, taking to the skies with one of the Blue Angels.
A Bay Area man discovered his devastating loss left him with a new opportunity to rethink how he lives -- follow his journey in virtual reality, 360-degree video.
A groundbreaking medical study involving the UCSF Medical Center has shown some colorectal cancer patients can safely skip radiation treatment and enjoy a potentially higher quality of life.
Every day, San Francisco bar pilot Captain Zach Kellerman goes through what might just be the world's most dangerous commute.
On Friday, expect cooler conditions, with highs ranging from the 60s along the coast, to about 90 inland. Additional cooling is expected this weekend. Zoe Mintz has the forecast.
A quarter century after the September 11 terror attacks, San Francisco Fire Chief Dean Crispen looks back at the aftermath, when he was part of a group of firefighters sent to Ground Zero to help. Kevin Ko reports.
Andrea Nakano reports.
Less than 10% of plastic ever gets recycled. The rest ends up in landfill, where it eventually breaks down into microplastics that get into the air, soil, and water.
Maddie White reports.
In 2025, KPIX is moving to a new community service award: the CBS News Bay Area Icon Award. Submit nominations for an outstanding community hero at kpix.com/icon.
It's the most wonderful time of the year for a South Bay woman who has played Mrs. Claus for more than 40 years for the children of North San Jose's Alviso District.
For residents of the Oakland Hills, the prospect of another wildfire always remains a concern. This week's Jefferson Awards winner has made it his mission to make the hills and other high-risk areas safer.
In East Palo Alto -- where state education numbers show more than nine in ten public school students are low income and more than half are English learners -- many are finding hope and connection at the Boys & Girls Clubs of the Peninsula.
This week's Jefferson Award winner is Army veteran who continues to live a life of service into his 80s, by feeding hundreds of San Francisco families a week.
A Bay Area man who overcame tremendous obstacles to excel in school has made it his mission to gear up other students for success in the classroom and in life.
For Students Rising Above scholar Josh Collins it took moving across the country to realize the value of his Bay Area family.
Samir Hooker had to grow up fast after his stepfather was shot dead 12 years ago. Now he is watching over his mom and sister while attending UC Berkeley.
It's hard enough to graduate from one of the most prestigious schools in the country when you're the first in your family to go to college. Imagine doing that while you're also trying to protect your parents from being deported?
Some students who are the first in their families to go to college face the challenge of balancing a rigorous academic load while still working to help support their family back home.