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The 49ers are been lucky enough to stay healthy so far this year and may have Ted Ginn Jr. back as early as Sunday. The Vikings on the other hands have players missing on both sides of the ball and will have to upset the 49ers and do it short handed.
The 49ers face the Vikings and Pro Bowl running back Adrian Peterson in Minnesota Sunday. Peterson is back after suffering a torn ACL and ruptured MCL in December, but John Madden expects him to seriously challenge the 49ers strong run defense.
The San Francisco 49ers are playing the Minnesota Vikings this week and if they stay focused they should cruise to the win. They will have to contain Minnesota running back Adrian Peterson, but for a team has such a strong defense this should not be a problem. The offense will stick to the same game plan it has used all season.
San Francisco 49ers Quarterback Alex Smith, who has worn a San Francisco Giants cap to post-game press conferences in recent years, could be slapped with a $15,000 fine by the NFL if he does it again, according to the Bay Area News Group.
With linebacker Clark Haggans' three-game suspension handed down by the NFL, San Francisco again needed to fill a void. This time they called Eric Bakhtiari who will have the chance to prove himself while Haggans is out. If he can make the most out of this chance, then Bakhtiari could find himself a member of the San Francisco 49ers for good.
ESPN's NFL Power Rankings have the 49ers looking down at the rest of the league. The team was a unanimous pick as they are miles in front of their competition in the early season. With a young team they are only poised to get better moving forward.
Vernon Davis has always been gifted, but until recently he had a "me first" attitude that was holding him back on the field. Thanks to the help of former coach Mike Singletary, Davis has matured into a role model in the community and has continued to flourish on the field. He had a record-breaking postseason last year and will play a huge role in the team's future success.
The San Francisco 49ers took the lead early and never looked back in their 27-19 win over the Lions. Led by Alex Smith, they scored just enough to keep the game out of reach and recovered an onside kick late to seal the win.
The 49ers dominated the Detroit Lions on both sides of the ball in a 27-19 victory at Candlestick Park Sunday.
San Francisco's stingy defense denied Matthew Stafford another milestone, Vernon Davis caught touchdown passes of 21 and 23 yards from Alex Smith, and the 49ers beat the Detroit Lions 27-19 on Sunday night in a September showdown of NFC powers.
Stocked with these gadgets, you'll be the most prepared 49ers fan at the tailgate.
The Week 2 injury report for both names lacked the big names that would concern the casual fan. However, the fact that so many Detroit defensive players are listed is not a good sign for a defense heading into a very physical game. There were two new names for the 49ers from Week 1 but both are expected to play on Sunday.
San Francisco 49ers fans thinking of heckling Detroit Lions supporters at Sunday's home opener should think twice.
The 49ers and the Lions meet on Sunday in a battle of two the NFC's best. The Lions are led by quarterback Matt Stafford and receiver Calvin Johnson on offense and their defense has one of the best defensive tackles in the game in Ndamukong Suh. While both teams are talented, the 49ers will be able to rely on their experience and mental toughness to wear out and outlast Detroit.
Last year's game ended with an angry exchange between the two coaches as they met at mid-field while the 49ers celebrated their victory.
Jauan Jennings agreed to one-year contract with the Minnesota Vikings to give the team a needed third option at receiver.
Netflix will air the Week 1 matchup between the San Francisco 49ers and Los Angeles Rams in Melbourne, Australia, a person familiar with the move told The Associated Press on Thursday.
Pinch-hitter Ty France delivered a two-run triple in the seventh inning to put San Diego ahead to stay as the Padres picked up a 5-1 win over the San Francisco Giants on Wednesday.
On what would have been his 95th birthday, a stretch of Interstate 80 in San Francisco has been officially renamed to honor San Francisco Giants legend Willie Mays.
With yet another top-five pick, GM Mike Grier and his staff can augment a young group already led by Macklin Celebrini and including Will Smith and Michael Misa.
Jackson Merrill had three hits and drove in two runs, Xander Bogaerts homered and the San Diego Padres tied their season highs for hits with 14 and runs in a 10-5 victory over the San Francisco Giants.
Jonathan Aranda hit a game-ending single in the 10th inning to cap a 4-for-5 afternoon, and the Tampa Bay Rays beat the San Francisco Giants 2-1 to complete a three-game sweep.
Jonathan Aranda hit a two-run single in Tampa Bay's three-run fifth inning and the Rays defeated the San Francisco Giants 5-1.
Cherie DeVaux became the first woman to train the winner of the opening leg of the Triple Crown.
Three separate incidents involving Oakland police officers unfolded over a 24-hour span this week, including an early Friday morning traffic stop that ended with an officer shooting a suspect after two other officers were dragged by a car.
A jury convicted a San Jose couple of murder for the 2023 fentanyl overdose death of their 19-month-old daughter, authorities said Friday.
Police activity along Interstate Highway 580 in Livermore led to the closure of all lanes in both directions as the weekend getaway commute on Friday afternoon was beginning.
A Northern California man was arrested on suspicion of human trafficking, illegal cannabis cultivation and other offenses after a worker reported he was forced to live and work at a cannabis growing site for two years.
A person was fatally shot in a Santa Clara neighborhood on Friday afternoon at a home doors away from another that later burned in a major fire, authorities said.
Officials in San Francisco have sued the owners of a convenience store in the city's Tenderloin, saying the establishment sold methamphetamine and cannabis, along with illegal tobacco products.
Police in San Francisco said a cold case involving a woman who disappeared more than 50 years ago has been solved, with the help of DNA.
Drivers who are planning to use 19th Avenue in San Francisco this Mother's Day weekend should expect delays, as southbound lanes of the roadway are closed for repaving work.
On what would have been his 95th birthday, a stretch of Interstate 80 in San Francisco has been officially renamed to honor San Francisco Giants legend Willie Mays.
Authorities on the Peninsula said five human trafficking survivors were rescued and one person was detained as part of a nationwide operation.
Three separate incidents involving Oakland police officers unfolded over a 24-hour span this week, including an early Friday morning traffic stop that ended with an officer shooting a suspect after two other officers were dragged by a car.
Police activity along Interstate Highway 580 in Livermore led to the closure of all lanes in both directions as the weekend getaway commute on Friday afternoon was beginning.
Two Oakland police officers and a suspect were taken to hospitals early Friday morning after a traffic stop in East Oakland ended in a shooting.
A man in distress was shot and killed by San Leandro police on Thursday evening after he pointed a gun at officers, police said.
A deadly attack in an Antioch neighborhood earlier this week has resulted in multiple felony charges including murder, attempted murder, kidnapping and child abuse charges, authorities said.
A jury convicted a San Jose couple of murder for the 2023 fentanyl overdose death of their 19-month-old daughter, authorities said Friday.
A person was fatally shot in a Santa Clara neighborhood on Friday afternoon at a home doors away from another that later burned in a major fire, authorities said.
The owner of a business on California's Central Coast has been arrested after he allegedly sexually assaulted a customer during what police described as a "spiritual cleansing."
During Asian American and Pacific Islander Heritage Month, we want to highlight the life and legacy of Japanese American Takayoshi "Dick" Miyagawa.
A man who shot a Mountain View police officer at point blank range during a traffic stop in 2022 was found guilty of attempted murder, authorities said.
A Northern California man was arrested on suspicion of human trafficking, illegal cannabis cultivation and other offenses after a worker reported he was forced to live and work at a cannabis growing site for two years.
Two former Rohnert Park police officers were sentenced to prison on Wednesday for their roles in a marijuana extortion scheme in which they posed as federal agents, prosecutors said.
Police in Santa Rosa have made one arrest and are looking for additional suspects following a shooting near a Cinco de Mayo festival Tuesday night.
In the North Bay, tractors have been commonly used to trim down dry brush, but grazing is now gaining popularity.
After years of devastating wildfires, droughts, and floods, many North Bay communities banned new gas stations as part of an effort to fight climate change. But the Town of Windsor may be making a U-turn.
Jauan Jennings agreed to one-year contract with the Minnesota Vikings to give the team a needed third option at receiver.
Netflix will air the Week 1 matchup between the San Francisco 49ers and Los Angeles Rams in Melbourne, Australia, a person familiar with the move told The Associated Press on Thursday.
Pinch-hitter Ty France delivered a two-run triple in the seventh inning to put San Diego ahead to stay as the Padres picked up a 5-1 win over the San Francisco Giants on Wednesday.
On what would have been his 95th birthday, a stretch of Interstate 80 in San Francisco has been officially renamed to honor San Francisco Giants legend Willie Mays.
With yet another top-five pick, GM Mike Grier and his staff can augment a young group already led by Macklin Celebrini and including Will Smith and Michael Misa.
Three separate incidents involving Oakland police officers unfolded over a 24-hour span this week, including an early Friday morning traffic stop that ended with an officer shooting a suspect after two other officers were dragged by a car.
A jury convicted a San Jose couple of murder for the 2023 fentanyl overdose death of their 19-month-old daughter, authorities said Friday.
A Northern California man was arrested on suspicion of human trafficking, illegal cannabis cultivation and other offenses after a worker reported he was forced to live and work at a cannabis growing site for two years.
A person was fatally shot in a Santa Clara neighborhood on Friday afternoon at a home doors away from another that later burned in a major fire, authorities said.
Two Oakland police officers and a suspect were taken to hospitals early Friday morning after a traffic stop in East Oakland ended in a shooting.
A system that thousands of schools and universities use was offline due to a cyberattack.
Netflix will air the Week 1 matchup between the San Francisco 49ers and Los Angeles Rams in Melbourne, Australia, a person familiar with the move told The Associated Press on Thursday.
A proposed $250 million settlement would compensate millions of consumers who bought the iPhone 16, iPhone 15 Pro or iPhone 15 Pro Max.
Career experts say workers and job seekers should take charge of their own AI education. Here's how to get started.
EBay said on Monday that it will "carefully review" GameStop's unsolicited $ 125-per-share takeover offer.
Mexican street corn-inspired trail mix made by Illinois food company was sold at Target and other retailers, as well as online.
A hospital in Santa Clara County is working to find the source of contamination that led to several people being infected by Legionella bacteria.
Three passengers have been evacuated from a cruise ship hit by a hantavirus outbreak, as related cases are confirmed in Switzerland and South Africa.
The FDA announced its first authorization of fruit-flavored electronic cigarettes intended for adult smokers, a major policy shift after months of appeals to President Trump from the vaping industry.
An ice cream company based in the San Francisco Bay Area is recalling dozens of products after they were sold without labels disclosing potentially dangerous allergens.
The U.S. military's latest strike on an alleged drug-trafficking boat in the eastern Pacific Ocean killed two men Friday while leaving one survivor.
Candidates for California governor were set to hold their final debate before the June Primary Election on May 14 in San Francisco.
The Trump administration announced a major expansion of its denaturalization campaign targeting foreign-born American citizens accused of fraudulently obtaining U.S. citizenship.
Defense Secretary Pete Hegseth said in a statement that the documents "have long fueled justified speculation — and it's time the American people see it for themselves."
The Justice Department argues the patchwork of state laws around guns makes it difficult to take them across state lines for lawful purposes like target shooting, hunting and self-defense.
Philz Coffee will once again sport the Pride flag at its cafés after a directive to have them and other flags removed created a backlash.
The Trump administration agreed to restore the Stonewall National Monument's Pride flag in Greenwich Village after it was removed.
Philz Coffee's move to remove the Pride flag and all other flags from their stores is brewing up some strong reaction.
Transgender women athletes are now excluded from women's events at the Olympics after the IOC agreed to a new eligibility policy on Thursday.
The Trump administration has given San Jose State University 10 days to change its policy on transgender athletes or face legal action and possibly lose federal funding.
Rihanna, Sabrina Carpenter, Madonna, and Beyoncé all wore their best looks to celebrate the "Costume Art" theme at the 2026 Met Gala. Here are some of the best moments, photos, and more from the night.
At Last Rites, the weekly gathering goes beyond simply watching a television show. For fans, it's an immersive experience, one that brings them closer to the world of "Survivor," and to each other.
Jake was at the funeral for one of his closest friends when he learned of his parents' deaths, he said.
Michael Tilson Thomas, the 12-time Grammy Award winning composer and famed conductor who led the San Francisco Symphony for a quarter century, has died.
Pop star Britney Spears has voluntarily checked into rehab following her DUI arrest in Ventura County in March, a representative for the singer told CBS LA.
Ever since the COVID-19 pandemic, the Oakland Unified School District has seen an alarming spike in the number of unhoused students in the school system who deal with a host of challenges far beyond what most children face.
Meteorologist and CBS News Bay Area's resident pilot Lt. Jessica Burch got a treat during Fleet Week, taking to the skies with one of the Blue Angels.
A Bay Area man discovered his devastating loss left him with a new opportunity to rethink how he lives -- follow his journey in virtual reality, 360-degree video.
A groundbreaking medical study involving the UCSF Medical Center has shown some colorectal cancer patients can safely skip radiation treatment and enjoy a potentially higher quality of life.
Every day, San Francisco bar pilot Captain Zach Kellerman goes through what might just be the world's most dangerous commute.
A person was fatally shot in a Santa Clara neighborhood on Friday afternoon at a home doors away from another that later burned in a major fire, authorities said.
Two Oakland police officers and a suspect were taken to hospitals early Friday morning after a traffic stop in East Oakland ended in a police shooting. Da Lin reports.
Despite reports of rising prices for Mother's Day gifts and outings, the Claremont Hotel in Berkeley is preparing for a busy weekend. Ryan Yamamoto reports.
With San Francisco facing a massive budget deficit, voters are being asked whether the city's largest companies should pay more. Supporters say Prop D will save services, while opponents say it will hurt the already struggling business community. Brad Hamilton reports.
Meteorologist Darren Peck says moderate heat will envelop the Bay Area and peak on Monday.
In 2025, KPIX is moving to a new community service award: the CBS News Bay Area Icon Award. Submit nominations for an outstanding community hero at kpix.com/icon.
It's the most wonderful time of the year for a South Bay woman who has played Mrs. Claus for more than 40 years for the children of North San Jose's Alviso District.
For residents of the Oakland Hills, the prospect of another wildfire always remains a concern. This week's Jefferson Awards winner has made it his mission to make the hills and other high-risk areas safer.
In East Palo Alto -- where state education numbers show more than nine in ten public school students are low income and more than half are English learners -- many are finding hope and connection at the Boys & Girls Clubs of the Peninsula.
This week's Jefferson Award winner is Army veteran who continues to live a life of service into his 80s, by feeding hundreds of San Francisco families a week.
A Bay Area man who overcame tremendous obstacles to excel in school has made it his mission to gear up other students for success in the classroom and in life.
For Students Rising Above scholar Josh Collins it took moving across the country to realize the value of his Bay Area family.
Samir Hooker had to grow up fast after his stepfather was shot dead 12 years ago. Now he is watching over his mom and sister while attending UC Berkeley.
It's hard enough to graduate from one of the most prestigious schools in the country when you're the first in your family to go to college. Imagine doing that while you're also trying to protect your parents from being deported?
Some students who are the first in their families to go to college face the challenge of balancing a rigorous academic load while still working to help support their family back home.
