Watch CBS News
Coach Jim Harbaugh on Friday praised the way his 2-2 team responded against the Rams and to the adversity and criticism it faced during a tumultuous stretch that included lopsided losses against Seattle and Indianapolis.
The San Francisco 49ers are paying Aldon Smith his normal salary even though the Pro Bowl pass rusher has left the team to begin his in-patient rehab following a second DUI arrest.
The 49ers are right back on their feet at 2-2, while the Rams have dropped three in a row since winning the opener for the first time since 2006 and have trailed by double digits in every game. Five reasons why the 49ers defeated the Rams...
The 49ers dominated the Rams in St. Louis Thursday night, winning 35-11. Frank Gore ran for 153 yards, but John Madden told the KCBS Radio morning crew that performance obscures a bigger achievement.
After scoring 10 points in the past two games combined, the 49er offense finally woke up. Frank Gore and Anquan Boldin lead the way as San Francisco snapped their first losing streak under Jim Harbaugh, exacting revenge on a St. Louis team that had the 49ers number last season.
Colin Kaepernick threw two touchdown passes, Frank Gore had his first 100-yard game of the season and the San Francisco 49ers' defense stepped up without some of their stars in a 35-11 rout over the St. Louis Rams on Thursday night.
Linebacker Patrick Willis and cornerback Nnamdi Asomugha were inactive for the San Francisco 49ers against the St. Louis Rams on Thursday evening.
The struggling 49ers face the Rams in St. Louis Thursday night.
Mired in their first losing stretch under coach Jim Harbaugh and minus at least one key player, the visiting 49ers look to avoid a third consecutive defeat Thursday night against a Rams team that gave them plenty of trouble in 2012.
"We're facing adversity. It gives us the opportunity to stare it in the face and respond," 49ers head coach Jim Harbaugh said. "That's a relentless quest for improvement, that's where we're at."
While it's hard to tell, the 49ers are slowly getting healthier. The long list of names on their injured report remains, but nothing to be alarmed about for the time being. St. Louis on the other hand is as healthy as can be heading into this pivotal game to stay out of the NFC West cellar.
One-fourth of the season will be over by the time the 49ers walk off the field in St. Louis, and if they do it as a 1-3 team, they will have dug themselves a hole that will be awfully hard to climb out from.
On their way to the Super Bowl last season, the San Francisco 49ers couldn't solve one team: the Rams. St. Louis beat San Francisco once and the teams played to a tie, rare blemishes on the 49ers' record.
In Week 1, San Francisco 49ers quarterback Colin Kaepernick set the world on fire with his passing against the Green Packers, throwing for 421 yards and basically convincing everyone he's the greatest quarterback in NFL history. The last two weeks? Yeah not so much.
While noting the 49ers lost to two very good teams in the Seahawks and Colts the last two weeks, Madden said those games exposed another 49er weakness.
The Valkyries are 11-6 on the road. Golden State ranks fourth in the Western Conference shooting 34.5% from 3-point range.
After becoming the first U.S. woman in more than two decades to win an individual Olympic gold medal in figure skating, Alysa Liu said she will take a break from competing.
The San Francisco 49ers held their final practice before their exhibition finale with nearly two dozen injured players missing but remain hopeful that most will be able to return to practice next week before the team departs for Australia for the season opener.
Rafael Devers hit his 28th homer, a drive that bounced into McCovey Cove, and Anthony Molina worked 4 1/3 scoreless innings as the San Francisco Giants beat the Cincinnati Reds 3-1.
San Francisco 49ers owner Jed York has pleaded no contest to two misdemeanor charges in Northeast Ohio after being arrested on suspicion of engaging in prostitution over the weekend, authorities said.
The rate is much higher than is seen in the general population. CTE is a brain disease linked to repeated blows to the head.
Rafael Devers hit a three-run homer in the second inning and the San Francisco Giants snapped a four-game losing streak by beating the Cincinnati Reds 5-0.
Cecilia Zandalasini scored eight of her 18 points in the fourth quarter, Gabby Williams added 15 points, and the Golden State Valkyries beat the Minnesota Lynx for the first time in franchise history.
The Red Sox came back to win and complete a three-game sweep of the Giants after falling behind, 3-0, early.
A toddler choking on a grape was saved by a Vallejo police officer who dislodged it from the child's throat over the weekend, the department said on Wednesday.
Pulitzer Prize-winning photographer Slava 'Sal' Veder, best known for his picture of a U.S. Air Force lieutenant colonel joyfully reuniting with his family after five years in a prisoner of war camp in Vietnam, died Aug. 22. He was 99.
The Valkyries are 11-6 on the road. Golden State ranks fourth in the Western Conference shooting 34.5% from 3-point range.
The San Jose Police Department provided a timeline Wednesday in the police shooting Tuesday evening south of downtown that left a suspect dead and an officer critically injured.
A new fire broke out in California's Big Sur Wednesday morning, as crews continued to battle a massive wildfire in the area that has burned for more than two weeks.
Adam Raine was 16 years old when he died by suicide. His parents say an AI chatbot guided him to the decision.
Transportation officials in San Francisco are investigating after video apparently showed a Muni metro train operator dozing off moments before a crash last month.
Users chat with an AI chatbot about what they're looking for, and Ditto handles the rest.
Two employees of a navigation center serving San Francisco's homeless population have been arrested for allegedly harboring a man charged in the shooting of a police officer, the department said.
A group of protesters who blocked San Francisco's Golden Gate Bridge in 2024 to protest Israel's war in Gaza were sentenced on Friday to one month in jail following their convictions on misdemeanor charges last month.
After becoming the first U.S. woman in more than two decades to win an individual Olympic gold medal in figure skating, Alysa Liu said she will take a break from competing.
The next chapter in the ongoing fight over Berkeley's Harrison Street encampment is taking shape.
A man acted alone when he randomly attacked five people across Oakland's Fruitvale neighborhood in a stabbing spree that police say lasted less than 30 minutes.
A man has been arrested for his alleged role in a deadly shooting outside an El Cerrito restaurant over the weekend, as police search for additional suspects in the case.
The air pollution from the Chevron Richmond Refinery carries levels of estimated cancer and short-term health risks above allowable levels, according to a new report from Bay Area air regulators.
The San Jose Police Department provided a timeline Wednesday in the police shooting Tuesday evening south of downtown that left a suspect dead and an officer critically injured.
A new fire broke out in California's Big Sur Wednesday morning, as crews continued to battle a massive wildfire in the area that has burned for more than two weeks.
Police in San Jose announced the arrests of three people suspected in a series of chain snatch robberies targeting elderly people and are searching for additional victims.
A San Jose transportation employee was killed Tuesday while performing repairs, officials said.
A San Jose police officer was hospitalized, and a suspect has died following a shootout south of the city's downtown Tuesday evening.
A toddler choking on a grape was saved by a Vallejo police officer who dislodged it from the child's throat over the weekend, the department said on Wednesday.
One year after a deadly apartment fire in San Rafael killed two women and two cats, the investigation into what happened remains ongoing, with the victims' families still waiting for answers.
As cities across California struggle to meet state housing goals, Habitat for Humanity Greater San Francisco is moving forward with plans to build what would become the largest affordable homeownership community in Marin County.
St. Helena residents say they are still dealing with discolored, foul-smelling water months after the city's water system came under scrutiny in a Napa County Civil Grand Jury report.
Drivers who rely on Interstate 80 between Solano County and the East Bay should expect delays this weekend, as Caltrans is set to close the westbound direction of the Carquinez Bridge for repaving.
The Valkyries are 11-6 on the road. Golden State ranks fourth in the Western Conference shooting 34.5% from 3-point range.
After becoming the first U.S. woman in more than two decades to win an individual Olympic gold medal in figure skating, Alysa Liu said she will take a break from competing.
The San Francisco 49ers held their final practice before their exhibition finale with nearly two dozen injured players missing but remain hopeful that most will be able to return to practice next week before the team departs for Australia for the season opener.
Rafael Devers hit his 28th homer, a drive that bounced into McCovey Cove, and Anthony Molina worked 4 1/3 scoreless innings as the San Francisco Giants beat the Cincinnati Reds 3-1.
San Francisco 49ers owner Jed York has pleaded no contest to two misdemeanor charges in Northeast Ohio after being arrested on suspicion of engaging in prostitution over the weekend, authorities said.
Police in San Jose announced the arrests of three people suspected in a series of chain snatch robberies targeting elderly people and are searching for additional victims.
A San Jose police officer was hospitalized, and a suspect has died following a shootout south of the city's downtown Tuesday evening.
A man acted alone when he randomly attacked five people across Oakland's Fruitvale neighborhood in a stabbing spree that police say lasted less than 30 minutes.
A man has been arrested for his alleged role in a deadly shooting outside an El Cerrito restaurant over the weekend, as police search for additional suspects in the case.
Authorities in the East Bay have arrested three people on suspicion of grand theft after thousands of cigarettes were stolen over the weekend, police said.
In a nearly 6,000-word essay, Gates argues that artificial intelligence poses a mounting threat to U.S. workers.
A plant in Southaven, Mississippi, that powers Elon Musk's SpaceXAI data centers in the area has sparked backlash from residents concerned about noise and air pollution.
Users chat with an AI chatbot about what they're looking for, and Ditto handles the rest.
Walmart will let shoppers use tap-to-pay methods, including Apple Pay and Google Pay, beginning later this month.
The Justice Department sued TikTok in 2024, alleging that it violated a U.S. law prohibiting the collection of kids' data.
Moderna and Merck announced study results that reflect a "landmark moment" in treatment for one of the deadliest forms of skin cancer.
Multiple unpermitted street food vendors in Fairfield were cited for violations last week after inspections found them selling food unsafe for public consumption, authorities said.
After weeks of uncertainty, students at Richmond's John F. Kennedy High School will start their classes on schedule after weeks after toxic chemicals were found underneath the campus.
Sunnyvale police raided smoke shops across the city and seized thousands of illegal products over the past two months, the city's Department of Public Safety said.
Despite a rash of foodborne illnesses in recent months, one expert said the nation's food supply is "remarkably safe." Here's what to know.
The group of 24 states and the District of Columbia argues the Postal Service's new rule violates the Constitution and federal law.
California lawmakers and Gov. Gavin Newsom are racing to reach a deal on changes to the state's wildfire liability system, with just days remaining before the legislative session ends.
Canadian government officials said they are also providing aid for workers and businesses that could be hurt by U.S.-imposed tariffs.
A federal judge on Tuesday rejected Ghislaine Maxwell's effort to toss out her 2021 conviction on sex-trafficking charges and 20-year prison sentence.
California lawmakers are pushing a package of energy bills aimed at lowering electricity costs and making clean energy more accessible as residents continue to face some of the highest utility rates in the country.
California Attorney General Rob Bonta has joined a coalition of 19 attorneys general in supporting a federal lawsuit challenging Idaho's law that bars transgender students from using school restrooms and other sex-separated facilities that align with their gender identity.
Berlin police did not identify the suspect, who is still at large, by name but said that he was already known to police and is from Berlin.
LGBTQ+ communities have significantly higher rates of unemployment than the general population. Kelsi Thorud reports on how the City of Oakland is empowering LGBTQ+ job seekers during Pride Month.
The fallout over the opposition by a handful of San Francisco Giants players against the team's Pride Night celebrations has prompted an investigation of Major League Baseball by the Trump administration.
Major League Baseball has warned players about writing on their uniforms after San Francisco starter Landen Roupp and two other pitchers added Bible verses to their Pride Night caps on Friday night.
The death of country music legend, actor, and philanthropist Dolly Parton at age 80 has Bay Area music stores scrambling to stock up for an expected rush to buy her music.
Tim Curry was known for his iconic performances in cult classics like "The Rocky Horror Picture Show" and the original screen adaptation of Stephen King's "It."
President Trump said that he would be "lowering the American flag" throughout the nation for one week in Dolly Parton's honor.
Dolly Parton became an icon over her six-decade career as a Grammy-winning singer-songwriter, movie and TV star and theme park owner who donated millions to help others.
Hayden Panettiere, who starred in "Remember the Titans" as a child actor and rose to fame in the series "Heroes," has died at the age of 36. The coroner's office says she was found in cardiac arrest.
Ever since the COVID-19 pandemic, the Oakland Unified School District has seen an alarming spike in the number of unhoused students in the school system who deal with a host of challenges far beyond what most children face.
Meteorologist and CBS News Bay Area's resident pilot Lt. Jessica Burch got a treat during Fleet Week, taking to the skies with one of the Blue Angels.
A Bay Area man discovered his devastating loss left him with a new opportunity to rethink how he lives -- follow his journey in virtual reality, 360-degree video.
A groundbreaking medical study involving the UCSF Medical Center has shown some colorectal cancer patients can safely skip radiation treatment and enjoy a potentially higher quality of life.
Every day, San Francisco bar pilot Captain Zach Kellerman goes through what might just be the world's most dangerous commute.
Thursday night's near total lunar eclipse will be the last one to view for the next three years. Brian Hackney reports.
Meteorologist Zoe Mintz says the marine layer will keep temperatures lower across the region, and has information on how to watch the upcoming lunar eclipse.
San Jose police revealed frightening new details on a shootout that left an officer critically hurt and a suspect dead. Brad Hamilton reports.
San Jose police provide an update on a shooting that happened Tuesday.
Dolly Parton music will be in high demand at Bay Are record stores following her death on Tuesday at the age of 80. Itay Hod reports.
In 2025, KPIX is moving to a new community service award: the CBS News Bay Area Icon Award. Submit nominations for an outstanding community hero at kpix.com/icon.
It's the most wonderful time of the year for a South Bay woman who has played Mrs. Claus for more than 40 years for the children of North San Jose's Alviso District.
For residents of the Oakland Hills, the prospect of another wildfire always remains a concern. This week's Jefferson Awards winner has made it his mission to make the hills and other high-risk areas safer.
In East Palo Alto -- where state education numbers show more than nine in ten public school students are low income and more than half are English learners -- many are finding hope and connection at the Boys & Girls Clubs of the Peninsula.
This week's Jefferson Award winner is Army veteran who continues to live a life of service into his 80s, by feeding hundreds of San Francisco families a week.
A Bay Area man who overcame tremendous obstacles to excel in school has made it his mission to gear up other students for success in the classroom and in life.
For Students Rising Above scholar Josh Collins it took moving across the country to realize the value of his Bay Area family.
Samir Hooker had to grow up fast after his stepfather was shot dead 12 years ago. Now he is watching over his mom and sister while attending UC Berkeley.
It's hard enough to graduate from one of the most prestigious schools in the country when you're the first in your family to go to college. Imagine doing that while you're also trying to protect your parents from being deported?
Some students who are the first in their families to go to college face the challenge of balancing a rigorous academic load while still working to help support their family back home.
