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There is going for a run in San Francisco, and there is running every single street in San Francisco. 37-year-old professional trail runner Rickey Gates is trying to do it in just six to seven weeks.
Faced with a spike in the number of empty storefronts in San Francisco, Mayor London Breed is vowing to cut the costs and the red tape for businesses to open new retail locations in the city's neighborhoods.
Peninsula-based action-camera maker GoPro says it will move production of U.S.-bound cameras out of China by the summer over tariff-related concerns.
After polling thousands of Bay Area radio listeners, San Francisco's KOIT radio station announced Monday it was returning the controversial 'Baby It's Cold Outside' holiday song to its daily playlist.
A 38-year-old woman was arrested after using counterfeit money to buy jewelry from a seller at the Alemany Farmers' Market in San Francisco on Sunday and then attacking the seller with scissors.
Fire crews quickly put out a two-alarm fire Sunday afternoon on Irving Street in San Francisco's Sunset District.
San Francisco has renamed Phelan Avenue to Frida Kahlo Way and city officials celebrated the occasion Friday with the unveiling of new street signs.
A search is on for a driver who caught another ride after his SUV veered off Highway 101 and landed in San Francisco Bay near Candlestick Point.
Doctors were stunned after a patient at UC San Francisco coughed up a six-inch blood clot that perfectly preserved the shape of his right bronchial tree.
Emergency planners are grappling with this question: if one accident can shut down the city's traffic flow for hours, what happens in major disaster?
In a 2-1 ruling late Friday, a panel of the 9th U.S. Circuit Court of Appeals in San Francisco said the ban is likely inconsistent with existing U.S. law.
Prosecutors say a man now charged with murder fatally stabbed a 16-year-old boy in the neck as the teen was filming a street fight Saturday night in San Francisco's Excelsior neighborhood.
The former site of the Fillmore West, where the San Francisco sound was cultivated by rock 'n' roll acts that went on to become legends, is slated to be demolished to make way for condos.
The family of a 21-year-old man killed by San Francisco police during an alleged shootout at an Excelsior District barbershop earlier this year has filed a wrongful death lawsuit against the city.
San Francisco City Attorney Dennis Herrera filed a lawsuit against a couple, accusing them of illegally taking advantage of the city's affordable housing program.
