Channing was 34 when she played tough Pink Lady Betty Rizzo in 1978's "Grease," opposite Olivia Newton John and John Travolta. CBS offered the actress two short-lived sitcoms in 1979 and 1980.
In 1999, she landed the role as First Lady Abbey Bartlet on "The West Wing," first sppearing as a recurring character before landing a regular role in 2001. During the 2005-2006 season she took another TV role, playing the wife of Henry Winkler in the CBS comedy "Out of Practice."
The series was canceled in May 2006, but she received an Emmy nod for the role in July. The actress has already won a bevy of awards, including two Emmys for her role as Abbey Bartlet.