So Vardalos took a break from acting to "grieve an infertility situation."
The 46-year-old actress-writer says she wrote six scripts during that time, and then she and her husband, Ian Gomez, adopted a 3-year-old girl.
Vardalos says her daughter, now 4 years old, is "definitely the best thing that ever happened to me." She adds: "And that's a big statement because a miracle happened with `My Big Fat Greek Wedding.' But career success means nothing without personal happiness."
Her latest film, "My Life in Ruins," opened Friday.