The case against Dr. Conrad Murray is complicated, involving drugs, dosages, medical protocols and other complex issues. Defense lawyers and prosecutors are crafting their legal strategies ahead of a summertime preliminary hearing where much of the evidence may become public.
Already, potentially damaging information about Murray has been revealed.
An autopsy report found Jackson died from an overdose of the powerful anesthetic propofol. In a statement to police, Murray acknowledged giving Jackson the drug and other sedatives to help him sleep, then briefly leaving his bedside. Cellular phone records show he made at least three personal calls around the time Jackson was stricken.
A Jackson employee who said he was in the room while Murray worked to save the pop star told police the doctor interrupted CPR to collect drug vials.
Murray maintains his innocence, and his lawyer, Ed Chernoff, has said nothing that he gave Jackson "should have" killed him. Chernoff noted the Jackson employee gave a different version of events to police in another statement.
"You may find after you are done watching the trial that it is not nearly as cut and dried as has been presented," Chernoff told The Associated Press in a recent interview. "One thing that simply will never be the truth is that Dr. Murray pumped a bunch of drugs into Michael Jackson and walked out of that room. He's not that kind of guy."
The King of Pop was 50 when he died on June 25 in his rented Bel Air mansion, on the brink of a series of comeback shows in London. Murray, a 57-year-old cardiologist with practices in Houston and Las Vegas, was hired by the superstar to look after his health during the rigorous rehearsals and planned to accompany Jackson to London.
Deputy District Attorney David Walgren will seek to prove the doctor acted with "gross negligence" when he gave the singer propofol to help him sleep.
The anesthetic is supposed to be used in hospital situations for surgery and patients are to be monitored constantly by anesthesia professionals. The drug's effects are intensified when used in conjunction with other sedatives.
Prosecution experts are expected to say it was reckless to use it in a private home without proper equipment.
TMZ has reported that among the defense strategies being discussed is the possibility Jackson administered the fatal dose himself. Chernoff declined to discuss how he might defend Murray and said a final decision won't be made until he hears the prosecution's theory at the preliminary hearing.
Regardless of what prosecutors present, he said there will be no plea bargain.
"Plea bargains are for guilty people," he said.
Realistically, there's little incentive for either side to push for a plea bargain.
Prosecutors brought a relatively minor charge with a maximum sentence of just four years, so there's not much room to negotiate down.
"The district attorney didn't overcharge the case," said celebrity attorney Harland Braun, whose clients included Dr. Allan Metzger of Los Angeles, an internist and rheumatologist who had a close relationship with Jackson and was godfather to one of the singer's children. "They are charging what they think they can prove."
Murray already is deeply in debt and pleading to a felony would open him to liability in a civil damages trial. The Jackson family has spoken of suing Murray for wrongful death.
To gain a conviction at trial, prosecutors will have to walk jurors through Jackson's complicated medical history as well as the events leading up to his death. That will be crucial, said Ellyn Garafalo, a prominent defense attorney who is representing a doctor charged in the Anna Nicole Smith drug case.
"The biggest hurdle they have is to show whatever Dr. Murray did caused Michael Jackson's death," she said. "They're going to have to say he knew or should have known that what he did could have resulted in death."
An element of the defense theory, Braun said, may be that Jackson was a demanding patient who insisted on propofol, a drug he had taken for a long time.
"The defense theory is Michael Jackson needed it, wanted it, knew the danger and took the risks," Braun said.
Garafalo said that while such an argument can be made in an effort to persuade the jury, it is not a legal defense.
"It's like saying I asked someone to shoot me and he did, so he's not guilty," she said.
Prosecutors will argue that the doctor bears the ultimate responsibility for his actions and can't be absolved because the patient may have pressured him to do something he should have known was dangerous.
Jackson's celebrity is sure to influence the case and Chernoff worries about seating a jury.
"There is a real concern that we have about getting a group of jurors that are going to come into court and are not going to have any preconceived notions of guilt," he said.
But publicity in this case is everywhere, he said, so seeking a change of venue is unlikely.
"The problem is we have this around-the-world stuff," said Chernoff. "Even in the O.J. Simpson trial, people in Uganda didn't care about it. But in this case, they care in Uganda and everywhere else."