Last Updated Dec 13, 2010 2:18 PM EST
Of course, you don't want to leave customers, clients, and colleagues in the dark. That's why it's essential to set up an e-mail auto-responder before you go.
If you're a Gmail user, the process couldn't be much simpler. Here's a 45-second tutorial:
If you're an Outlook user, be sure to check out Dave's awesome how-to video on setting up e-mail auto-responders in Outlook.