But this most public of performers and pop sensation has somehow maintained a certain level of privacy over her personal life - until "60 Minutes" came by.
In a revealing interview airing on the CBS News broadcast Sunday, CNN's Anderson Cooper introduces viewers to the person behind the performer.
She tells Cooper she.
"The Early Show" had a preview of the interview on Friday:
The pressures of maintaining fame and the deadly price other superstars have paid for it are frequent themes in Lady Gaga's performances, Cooper observes.
"That's what everyone wants to know, right?" Gaga observed. "What's she gonna look like when she dies? What's she gonna look like when she's overdosed on whatever they think I'm overdosing on? Everybody wants to see the decay of the superstar."
"Do you think people wanna see your decay?" Cooper asked.
"What? Of course they do," Gaga replied. "They wanna see me fail, they wanna see me fall on stage, they wanna see me vomiting out of a nightclub. I mean, isn't that the age that we live in? That we wanna see -- people who have it all lose it all? I mean, it's -- it's dramatic. And it's…"
"And then climb their way back," Cooper interjected.
"Right. It's a movie," Gaga responded. "And -- and yet I just am not like that on -- on my own time. … I'm not a vomit in the club kind of girl."
Gaga also told Cooper to call her -- Gaga -- but said she likes to be called by her given name -- Stefani -- in bed.
You can see the entire interview on "60 Minutes" Sunday a 7 p.m. EST, 6 p.m. Central, on CBS.