The squid showed up last week and anglers started booking twilight fishing trips over the weekend to catch them.
The animals weigh between 20 and 40 pounds, but a few fishermen have reeled in 60-pound creatures.
The Humboldt squid is also called the jumbo squid or jumbo flying squid and squirts ink to protect itself.
They can grow up to 100 pounds and 6 feet long and follow food sources. The squid have also recently been spotted off San Diego, Oregon and Washington, all on the U.S. West Coast.
Robert Woodbury with Newport Landing Sportfishing told The Orange County Register that anglers in the Southern California county have caught about 400 of the big squid since Friday night.