The arrest comes about two months before he faces a trial on a DUI manslaughter charge.
Broward County Jail spokeswoman Keyla Concepcion said Leyritz was booked Thursday morning after an incident in Davie, a Fort Lauderdale suburb. She could not provide additional details.
The 45-year-old Leyritz played for six teams in 11 seasons. During a stint with the New York Yankees, he hit a memorable home run in the 1996 World Series to help the Yankees win Game 4 against Atlanta.
Police say Leyritz was drunk when he caused a fatal car crash in December 2007. He is scheduled to go on trial in September.
Leyritz's attorney did not immediately return a message.