"Stand Up to Cancer" telecast returning Sept. 5

Gwyneth Paltrow attends the Stand Up To Cancer benefit at The Shrine Auditorium on Sept. 7, 2012, in Los Angeles.

Getty Images

Building on its three historic fundraising telecasts in 2008, 2010 and 2012, Stand Up to Cancer is returning to primetime television this fall.

Dozens of broadcast and cable networks will again donate a simultaneous hour of commercial-free airtime to carry the fundraiser on Sept. 5 at 8 p.m. ET.

Participants will include ABC, CBS, Fox, NBC, HBO, E!, Showtime, Lifetime, ESPNews and many others. A Canadian broadcast is being added this year.

Gwyneth Paltrow and Joel Gallen are returning to produce the telecast for a second time, and other stars from television, film and music will encourage and accept donations from the public. The money raised supports cross-disciplinary research toward new cancer treatments.

"Cancer profoundly touched my life when I lost my father to the disease twelve years ago, and Stand Up To Cancer gives me a powerful platform to fight for a cause that I'm passionate about," Paltrow said in a news relesae. "I am thrilled to join Joel Gallen to executive produce the Stand Up To Cancer telecast again this year, and honored to continue standing up in my father's memory."

During this year's broadcast, celebrities will use an on-stage digital lounge to interact with viewers via social media. Viewers will be able to donate via a toll-free number, standup2cancer.org and text-to-give, with 100 percent of the donations received from the public during the show going to support collaborative cancer research programs.