On Friday, Penn's relief organization JP HERO took over the management of a camp of 40,000 quake survivors.
The camp is on the ground of the Petionville club golf course, where Penn and volunteers of his organization spend days and nights offering relief to Haitians who lost their homes in the earthquake.
Haiti, the Western Hemisphere's poorest nation, was struck by a Jan. 12 earthquake that killed at least 217,000 people, destroyed about 255,000 houses and left one million homeless, Haitian President Rene Preval has said.
Penn said he didn't think twice before helping Haiti.
"It was kind of like putting a quarter on a railroad track and then you look up and see the train coming and you start running and you find yourself in a tunnel and you just have to keep going, get out on the other side," Penn said.
JP HERO said it has treated more than 55,000 patients, distributed over 50,000 lbs. of rice and other food items and helped 42 orphans to be evacuated to the United States.
It currently serves 2,000 meals a day to earthquake victims and volunteers, JP HERO said.