Addressing a small crowd of American citizens at the King David Hotel, Romney noted that during his business career he had been interested in the economic disparities among nations.
"As you come here and you see the GDP per capita for instance in Israel, which is about $21,000, and you compare that with the GDP per capita just across the areas managed by the Palestinian Authority, which is more like $10,000 per capita, you notice a dramatic, stark difference in economic vitality," he said. "And that is also between other countries that are near or next to each other."
First of all, Romney underestimated Israel's annual per capita GDP -- which a U.N. website lists as $27,060 for 2009 (the most recent data available) -- and he grossly overestimated the figure for the Palestinian-controlled West Bank and Gaza Strip, which the U.N. shows as $1,367 (also as of 2009).
(Watch a clip of CBS News' Jan Crawford's recent interview with Romney.)
But the portion of Romney's remarks that drew the biggest reaction came when he noted that he had read several books related to economic disparity among nations, including "Guns, Germs, and Steel" (which attributes such differences largely to geographical circumstances) and "The Wealth and Poverty of Nations" (which credits differences in culture for these disparities).
Romney left no doubt where he stands on this question: "Culture makes all the difference. And as I come here and I look out over this city and consider the accomplishments of the people of this nation, I recognize the power of at least culture and a few other things."
This is a topic Romney addressed in his 2011 book, "No Apology," and one that was a major point of emphasis in the stump speech he delivered many dozens of times during his 2008 presidential run. Yet his decision while in Jerusalem to apply this broad concept to the complicated and sensitive dynamics of the Israeli-Palestinian relationship led him into another thicket.
Romney's comments drew a stinging rebuke from Saeb Erekat, a top aide to Palestinian President Mahmoud Abbas, who unloaded on the presumptive Republican presidential nominee in an interview with the Associated Press.
"It is a racist statement, and this man doesn't realize that the Palestinian economy cannot reach its potential because there is an Israeli occupation," Erekat said. "It seems to me this man lacks information, knowledge, vision, and understanding of this region and its people."
(Romney delivers a speech in Jerusalem on Sunday.)
Romney met with Palestinian Prime Minister Salam Fayyad on Sunday night but did not convene with Abbas during his trip to the region.
Romney campaign spokesperson Andrea Saul said that the candidate's remarks had been "grossly mischaracterized," and aides to the former Massachusetts governor noted that his description of disparities among other neighboring countries showed that his comments were part of a broader point he was making.
Just days after Romney drew scorn from the British media and some public officials for echoing widespread concerns about preparations for London Olympic Games, his characterization of a touchy economic matter served as another reminder that every utterance a potential commander-in-chief makes while on foreign soil will be carefully examined.