As Huffington Post first reported, Fiorina was asked on St. Louis KTRS Radio if she believes Palin "has the experience to run a major company, like Hewlett Packard."
"No, I don't," Fiorina replied. "But you know what? That's not what she's running for."
Asked about the comment later on MSNBC, Fiorina made a similar statement about the man at the top of the Republican ticket.
"Well, I don't think John McCain could run a major corporation," Fiorina said.
She continued: "I don't think Barack Obama could run a major corporation. I don't think Joe Biden could run a major corporation. But on the other hand, a major corporation is not the same as being the president or vice president of the United States. It is a fallacy to suggest that the country is like a company. So, of course, to run a business you have to have a lifetime of experience in business. But that's not what Sarah Palin, John McCain, Barack Obama or Joe Biden are doing."
Fiorina's is the second statement from a McCain adviser today that the campaign likely wishes it could take back. Earlier, economic advisor Douglas Holtz-Eakin suggested that McCain helped create the BlackBerry communications device, a comment later dismissed as a "boneheaded joke" by a McCain aide.
"If John McCain's top economic advisor doesn't think he can run a corporation, how on Earth can he run the largest economy in the world in the midst of a financial crisis?" Obama campaign spokesman Tommy Vietor said in a statement. "Apparently even the people who run his campaign agree that the economy is an issue John McCain doesn't understand as well as he should."