What's it like to be the "arm candy" in the relationship?
Colbert brought up Clooney's marriage to human rights lawyer Amal Clooney, asking "What is it like to be the arm candy in a relationship, because she's the very serious person?" The host added, "She must say like, 'We're going to meet extremely intelligent people tonight - these are not show folk. Just be shiny and pretty."
"That's mostly what I do," Clooney responded.
Colbert also congratulated the actor on his upcoming 1-year wedding anniversary on Sept. 27.
Clooney's response? "They said it wouldn't last."
CBS' new late-night host even had a little gift for the power couple: a paperweight from Tiffany's with the engraving, "I don't know you."
The interview didn't solely focus on Clooney's love life, though. The pair also did a funny bit about a fake movie called "Decision Strike."
Check it out below: