One person died and 13 were hospitalized, many with major injuries, after Wednesday's crash. A 27-year-old man faces charges of murder and attempted murder, Deputy Police Chief Greg McCurdy said.
"It appears he did this intentionally. The reason is questionable," McCurdy said Thursday.
The man, Stephen Michael Ressa of Rialto, Calif., had also been sought by his hometown police in a near-fatal assault Monday on his mother, who owned the car Ressa was driving in Las Vegas.
The victims, including 11 tourists, were walking in front of the Bally's and Paris hotel-casinos on Wednesday when the car struck them, then crashed into a wall and came to a stop in a landscaped area in front of Bally's.
The injured were strewn along the sidewalk and were being treated in the street by emergency personnel as stunned tourists looked on. Traffic on the Las Vegas Strip was stopped for almost five hours.
Ressa was unhurt and was arrested at the scene by an off-duty officer, police said.