Barbra Streisand opens her home for women's heart health

Former President Bill Clinton, right, poses with Barbra Streisand, center, and her husband James Brolin at the dedication of the Barbra Streisand Women's Heart Center in the Cedars-Sinai Heart Institute, on Thursday June 14, 2012 at Streisand's home in Malibu, Calif. (Photo by Chris Pizzello/Invision/AP)
Chris Pizzello
Former President Bill Clinton poses with Barbra Streisand and her husband, James Brolin, on June 14, 2012, at Streisand's home in Malibu, Calif.
Chris Pizzello

(CBS/AP) Barbra Streisand sang and former President Bill Clinton spoke to a Hollywood crowd gathered to raise funds for women's heart health on Thursday.

Comedian Martin Short was the master of ceremonies at the intimate fundraising dinner at the Malibu, Calif. ,home Streisand shares with her husband,  actor James Brolin.

Pictures: Streisand sings

Guests paid as much as $100,000 per couple to attend the event supporting the Barbra Streisand Women's Heart Center at Cedars-Sinai Medical Center. Streisand donated $10 million to the new research-and-treatment facility and solicited million-dollar donations from wealthy friends she called personally.

"I endowed the program for every woman and for every man who has a woman in his life -- his daughter, his wife, his sister or mother," Streisand told The Hollywood Reporter.

On Thursday night, Streisand performed four songs for guests, including designer Donna Karan, Viacom Chairman Sumner Redstone, NBCUniversal chief Ron Meyer and actors Josh Brolin and Diane Lane.

Josh Groban sang before Streisand took the stage to perform a program  that  included the Oscar- and Grammy-winning "Evergreen," which she dedicated to Clinton. He told her in 1992 that it was his favorite song of hers, and she sang it at his inauguration.

She and Groban performed"Smile" as a duet, and Streisand closed the evening with a special rendition of "Here's to Life" with new lyrics by Alan and Marilyn Bergman, who were also among the guests.

Heart disease kills more women each year than all cancers combined, but most of the research on the disease for the last five decades has been conducted on men.

"Even in scientific research, women are still treated as second-class citizens," Streisand said, "and to me, that's just unacceptable."

So she raised her voice and opened her wallet and invited her friends to do the same.

"It's kind of a selfish thing because it's actually very fulfilling to do something like that that's larger than me or my career," she said, acknowledging that her fellow donors must feel the same way.