Last Updated Jun 13, 2016 12:20 PM EDT
The massacre at the Pulse nightclub in Orlando overnight was the deadliest mass shooting in U.S. history, with at least 49 people dead (plus the gunman) and another 53 wounded. News of shooting incidents at everyday places like offices, schools and shopping malls seem to have become numbingly common, and a 2014 FBI study found that the number of mass shootings has increased in recent years.
Here is a look at the some of the worst mass shootings this country has seen.
Orlando, Florida - Pulse nightclub - At least 49 dead
June 12, 2016: A gunman armed with an assault-type rifle and a handgun opened fire inside a crowded gay nightclub in Orlando in a rampage and hostage standoff that lasted three hours before he was killed in a gunfight with SWAT officers, police said. The gunman was identified as 29-year-old Omar Mateen. The attack is being investigated as a possible act of terrorism.
Blacksburg, Virginia - Virginia Tech - 32 dead
April 16, 2007: Seung-Hui Cho, 23, killed 32 people in two shooting scenes at a dorm and then in a classroom building on the Virginia Tech campus in Blacksburg, Virginia. He then killed himself.
Newtown, Connecticut - Sandy Hook Elementary School - 27 dead
Dec. 14, 2012: Adam Lanza, 20, opened fire at Sandy Hook Elementary School, killing 20 children and six staff members before killing himself. His mother, Nancy Lanza, was also found shot to death at their home.
Killeen, Texas - Luby's Cafeteria - 23 dead
Oct. 16, 1991: Twenty-three people were killed and 20 more wounded when George Hennard opened fire at Luby's Cafeteria. He then killed himself.
San Ysidro, California - McDonald's - 21 dead
July 18, 1984: James Oliver Huberty, an out-of-work security guard, killed 21 people in a McDonald's restaurant in San Ysidro, California. A police sharpshooter killed Huberty.
Austin, Texas - University of Texas - 16 dead
Aug. 1, 1966: Charles Whitman killed his wife and mother, then opened fire from the clock tower at the University of Texas at Austin, killing 16 people and wounding about 30 others before he was shot and killed by police.
San Bernardino, California - 14 dead
Dec. 12, 2015: Syed Farook and his wife Tafsheen Malik opened fire on a meeting and holiday lunch for Farook's colleagues in San Bernardino, killing 14 in a terrorist attack inspired by ISIS. They died in a shootout with police hours later.
Edmond, Oklahoma - 14 dead
Aug. 20, 1986: Pat Sherrill, 44, a postal worker who was about to be fired, shot and killed 14 people at a post office in Edmond, Oklahoma, then killed himself.
Fort Hood, Texas - 13 dead
Nov. 5, 2009: Thirteen soldiers and civilians were killed and more than two dozen wounded when a gunman walked into the Soldier Readiness Processing Center at Fort Hood, Texas, and opened fire. The gunman, Maj. Nidal Hasan, an Army psychiatrist, was convicted on 13 counts of premeditated murder and sentenced to death.
Littleton, Colorado - Columbine High School - 13 dead
April 20, 1999: Students Eric Harris, 18, and Dylan Klebold, 17, opened fire at Columbine High School in Littleton, Colorado, killing 12 classmates and a teacher and wounding 26 others before killing themselves in the school's library.
Binghamton, New York - 13 dead
April 3, 2009: A gunman identified as 41-year-old Jiverly Wong opened fire in a community center where immigrants were taking a citizenship exam in Binghamton, in upstate New York, killing 13 people before committing suicide.
Seattle, Washington - 13 dead
Feb. 18, 1983: Three gunmen opened fire at the Mah Wee gambling and social club in Seattle's Chinatown neighborhood, killing 13. The suspects escaped but were captured, tried and convicted.
Wilkes-Barre, Pennsylvania - 13 dead
Sept. 25, 1982: Former prison guard George Banks shot and killed 13 people, including 4 of his own children. He was sentenced to death but remains behind bars amid questions about his mental competency.
Camden, New Jersey - 13 dead
Sept. 6, 1949: In one of the first modern mass shooting incidents in U.S. history, Howard Unruh shot and killed 13 people as he walked down the streets in Camden, New Jersey. He was found to have paranoid schizophrenia and spent the rest of his life in a mental hospital, dying in 2009.
Aurora, Colorado - Movie theater - 12 dead
July 20, 2012: A dozen people were killed when a gunman burst in and opened fire during a midnight screening of the Batman movie "The Dark Knight Rises." James Holmes, 24, pleaded not guilty by reason of insanity. He was convicted and sentenced to life in prison.
Washington, D.C. - Navy Yard - 12 dead
Sept. 16, 2013: Former contractor Aaron Alexis shot and killed 12 people and wounded eight at the Washington Navy Yard before dying in a shootout with police. He was reported to have had a history of mental illness.