Last Updated Feb 7, 2016 7:08 PM EST
The NFL's biggest game may be turning 50, but it's showing no signs of slowing down with age.
In Super Bowl 50, Denver Broncos quarterback Peyton Manning, who's likely bound for the Pro Football Hall of Fame, will suit up for his fourth Super Bowl and what he said may be his "last rodeo." He'll face off against Carolina Panthers play-caller Cam Newton, a young gun who led his team on an onfield-celebration-filled run to a nearly undefeated regular season.
Like Super Bowl XLIX last year, this big game isn't without controversy. While the days of "Deflategate" are over, the NFL is conducting an investigation into a controversial report that linked Manning to human growth hormone, a banned performance-enhancing drug.
"I can tell you what they're going to find: a big fat nothing," Manning told CBS Sports analyst Bill Cowher of "The NFL Today." "It's been completely fabricated as far as the allegations of what they suggested that I did. It's been nothing but pure junk, and I welcome that investigation."
Manning and the Indianapolis Colts won Super Bowl XLI in 2007. This is Newton's first shot at the Vince Lombardi Trophy.
As with every Super Bowl, not all of the action will be while the clock is running. The NFL announced that the national anthem performer will be Lady Gaga, a decidedly more notable artist than the bands for the universities of Arizona and Michigan, which performed "The Star-Spangled Banner" at Super Bowl I.
Beyonce and the British band have worked together before, appearing in a video released recently for the band's song "Hymn for the Weekend" on its new album, "A Head Full of Dreams."
And then there are the commercials. Natalie Zmuda, managing editor of Advertising Age, said on "CBS This Morning" Wednesday that viewers should expect to see a lot of celebrity appearances and attempts at humor after last year's so-called "Somber Bowl," which featured spots of a more serious nature.
For Super Bowl 50, Willem DaFoe, Drake, Seth Rogen and Amy Schumer have already appeared in ads that were released in the days leading up to the game.
Super Bowl Sunday
Carolina Panthers vs. Denver Broncos
- Kickoff: 6:30 p.m. ET
- Pregame coverage: 11 a.m. ET
- TV: CBS
- Online: CBS Sports will stream its pregame coverage starting with "The Super Bowl Today" at 2 p.m. ET, which can be seen on computers and tablets at CBSSports.com and on the home entertainment devices Android TV, Apple TV, Roku and Xbox One. The game, all of the commercials and the halftime show will be streamed.
- Spanish simulcast: ESPN Deportes will broadcast the game in Spanish. The simulcast will be streamed on WatchESPN.