Updated 10:03 PM ET
The Senate easily confirmed President Barack Obama's selection for U.S. ambassador to the United Nations on Thursday, capping a month in which senators used a bipartisan truce on once-mired nominations to fill a cluster of vacancies in the president's second-term administration.
Senators approved Samantha Power for the post by 87-10. The vote put the former Obama foreign policy adviser and outspoken human rights advocate into the job formerly held by Susan Rice, whom the president has made his national security adviser.
"As a long-time champion of human rights and dignity, she will be a fierce advocate for universal rights, fundamental freedoms and U.S. national interests," Obama said in a written statement after the vote.
The Irish-born Power, a one-time journalist who also has a Harvard Law School degree, has reported from many of the world's trouble spots and won a 2003 Pulitzer Prize for a book on the meek U.S. response to many 20th century atrocities, including those in Rwanda and Bosnia in the 1990s. She has long backed intervention - including military force - to halt human rights violations.
Powers has been "a tireless defender of human rights," said Senate Foreign Relations Committee Chairman Robert Menendez, a Democrat. "She has seen the tragedy of human suffering from the front lines, first hand."
Speaking against her nomination was Sen. Marco Rubio, a Republican and possible 2016 presidential candidate..
He said the next U.N. ambassador must focus on making sure the world organization is "more accountable, that it is more effective and that it is just not some multilateral ideal in which we invest all of our hopes." He said he doubted the administration's and Power's willingness to do that.
Power's penchant for outspokenness has included her 2002 call for a "mammoth protection force" to prevent Middle East violence, from which she has distanced herself.
Two weeks ago, Venezuela said it was calling off efforts to restore normal relations with the U.S. after Power said at her Senate confirmation hearing that the South American country was guilty of a "crackdown on civil society."
She also called the U.N.'s inaction to end the large-scale killing in Syria's civil war "a disgrace that history will judge harshly."
Power joined a stack of nominees that senators have approved since striking a bipartisan deal in mid-July. Late on Thursday, the Senate also confirmed:
-Army Gen. Martin Dempsey for another two-year term as chairman of the Joint Chiefs of Staff, and Adm. James Winnefeld, the vice chairman of the Joint Chiefs.
-Jason Furman, a veteran White House economic official, as chairman of the president's Council of Economic Advisers.
-Michael Sean Piwowar of Virginia, Kara Marlene Stein of Maryland and Mary Jo White of New York to the Securities and Exchange Commission.
-James Costos of California as U.S. ambassador to Spain.
Republicans agreed to allow votes on seven of Obama's picks after Democrats agreed to drop plans to invoke the so-called nuclear option, forcing Senate rules changes that would have made it harder for the chamber's minority parties to block some nominations.
Over the past three weeks, senators have approved Obama's choices to head the Environmental Protection Agency, the FBI, the Consumer Financial Protection Bureau and other agencies.
With Congress about to start a summer recess, many leaders are hoping that the bipartisan cooperation will survive into the fall, when lawmakers face nasty fights over the budget, immigration and other issues.
Underscoring the limits of the truce on nominations, all but one Republican banded together earlier Thursday to prevent the Senate from debating a $54 billion measure financing transportation and housing programs. That dispute evoked partisan passions on both sides, with Republicans accusing Democrats of busting budget limits and Democrats saying the GOP was bowing to extremists.