Rare disease or fake illness?
Dr. William Gahl, director of the Undiagnosed Diseases Program at the National Institutes of Health, explains why mysterious ailments are sometimes mistaken for hypochondria.
Rare Disease Day
Hard cases: Investigating rare & tough diseases
Dr. William Gahl is one of the last, best hopes for people suffering from rare, debilitating, and undiagnosed medical conditions. Lara Logan reports.
Stop FOP: Man's rare disease turns muscle to bone
20-year-old college student raises awareness for rare disease with only 800 confirmed cases worldwide
The battle to research rare diseases
Incentives have encouraged rare disease research but lack of funding, high cost of medication provide challenges
Rare Disease Day: Handprints across America
An estimated 30 million Americans suffer from one of 7,000 rare diseases, many of which can't be treated
Hard cases: Investigating rare & tough diseases
Dr. William Gahl is one of the last, best hopes for people suffering from rare, debilitating, and undiagnosed medical conditions
Rare Disease Day spotlights need for treatments
National Organization for Rare Disorders was founded in 1983 along with Orphan Drug Act - has progress been made?
Doctors plug unstoppable nosebleed with cured pork
Girl had rare blood disorder Glanzmann's thrombasthenia, so do not try at home
6-year-old girl saved by rare organ transplant
Angela Bushi was diagnosed with rare Wolcott-Rallison Syndrome, needed pancreas, liver, and two kidneys to survive
"Bucket List" baby Avery Canahuati dies
5-month old girl's family started Avery's Bucket List blog to spread awareness about rare disease, spinal muscular atrophy
7-year-old Colorado girl contracts bubonic plague
About 7 cases of plague, which is transmitted to humans through infected fleas or bites from infected animals, are reported in the U.S. annually
3-D printer gives use of arms to 4-year-old
Girl had rare condition that causes abnormal development of muscles and was unable to use her arms
First treatment for progeria shows promise
Patients in study had improved cardiovascular health and were able to gain weight, two problems associated with the disease
17-year-old Pa. woman battles "Sleeping Beauty Syndrome"
Nicole Delien diagnosed with Kleine-Levein Syndrome; She once slept 64 days from Thanksgiving through January
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Former model with rare growth disease dies
Acromegaly is a disorder in which there is too much growth hormone in the body
Dad's death shines light on rare Loeys-Dietz syndrome
Dad's death from rare heart condition, Loeys-Dietz syndrome, led to a diagnosis of the disease in his twin daughters
Man without legs climbs Mt. Kilimanjaro
Climber Spencer West was born with sacral agenesis, a rare condition in which the lower spine, pelvis don't form properly at the time of birth
Clara's journey: 9-year-old with deformed face navigates the world
Clara Beatty was born with rare genetic mutation called Treacher Collins syndrome, causing deformed face
Amelia Rivera, 3, in struggle for kidney transplant over disability
Controversy sparked in January when Riveras said prominent hospital denied daughter kidney transplant because of disability
World's friendliest kids? Gene disorder means extreme sociability
Williams syndrome has been likened to having "joy gene," but what's life been like for Williams patient Ben Monkaba?
Proteus syndrome: The Elephant Man and beyond
Up close and personal with disorder that can be as disfiguring as it is rare
HealthWatch
Measles cases at university in Florida soar to nearly 60
Twenty one states in the U.S. have confirmed cases of measles.
Can TrumpRx help you save money on drugs? Here's what experts say.
The Trump administration's new discounted drug platform, TrumpRx, isn't a game-changer for consumers, health care experts said.
Moderna says FDA refuses its application for new mRNA flu vaccine
The Food and Drug Administration is refusing to consider Moderna's application for a new flu vaccine made with mRNA technology, the company said.
What to know about a new study on coffee, tea and dementia risk
CBS News medical contributor Dr. Céline Gounder said the results of the study on coffee drinkers having lower risk of dementia should be taken "with a massive grain of salt."
Thousands of mothers were flagged to police over flawed drug tests at childbirth
The Marshall Project found more than 70,000 cases referred to law enforcement over allegations of substance use during pregnancy — and that's a significant undercount.
Obamacare sign-ups drop, but the extent won't be clear for months
Experts say Affordable Care Act sign-up data won't be clear until people who were enrolled have paid — or not — their new, often much higher, premiums.
Hospital flooded by Hurricane Helene to be rebuilt in another flood plain
Ballad Health, the nation's largest state-sanctioned hospital monopoly, plans to rebuild Unicoi County Hospital in Tennessee on land that two climate modeling companies say is at risk of flooding.
Her deadly diagnosis only had 1 warning sign. Here's how she survived.
Becca Valle, then 37, enrolled in a cutting-edge clinical trial after surgery removed an aggressive tumor from her brain.
California urges avoiding wild mushrooms after deaths, liver transplants
More than three dozen cases of death cap mushroom poisonings have been reported in California since November, health officials said.
U.S.
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No DNA match in database from profile recovered during Nancy Guthrie search
The DNA profile was recovered during the investigation into the disappearance of Nancy Guthrie in Arizona.
Tricia McLaughlin, top Homeland Security spokeswoman, leaving her post
Tricia McLaughlin, the Department of Homeland Security's top spokeswoman, is leaving her post next week, two U.S. officials familiar with her plans told CBS News.
Epstein survivor tells CBS News how she was trafficked, and assaulted
Juliette Bryant says not long after meeting Jeffrey Epstein, he assaulted her, and she realized, "this is not a modeling opportunity, I've been kidnapped."
Trump honors Jesse Jackson as "force of nature"
President Trump and the Rev. Jesse Jackson, who died Tuesday at the age of 84, knew each other for decades.
Democrats make counteroffer on ICE reforms as DHS shutdown continues
Democrats made their counteroffer on overhauling immigration enforcement on Monday, the latest step in talks to fund the Department of Homeland Security.
MoneyWatch
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Warner Bros. Discovery restarts takeover talks with Paramount Skydance
Warner Bros. Discovery said that Paramount Skydance is considering enhancing its buyout offer for the entertainment company.
Why athleisure giant Lululemon is losing momentum
After a decade of rapid growth, Lululemon is struggling to find its footing in an increasingly saturated market.
Average tax refund is nearly 11% higher so far this year, IRS data shows
Forecasters predicted filers would benefit from larger checks this year due to a series of new tax provisions in the "one big, beautiful" bill.
What's open and closed on Presidents Day 2026?
Most retail and food establishments will remain open, but services like mail delivery will be suspended for the federal holiday.
Prediction markets heat up on Valentine's Day as people place bets on love
Prediction markets are taking bets this Valentine's Day that celebrity relationships can thrive — or break apart.
Politics
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Hillary Clinton alleges Epstein files "cover-up" by Trump administration
"There's something about this administration's attitude toward this, which I think really leads us to conclude they have something to hide," she told the BBC.
Tricia McLaughlin, top Homeland Security spokeswoman, leaving her post
Tricia McLaughlin, the Department of Homeland Security's top spokeswoman, is leaving her post next week, two U.S. officials familiar with her plans told CBS News.
Trump honors Jesse Jackson as "force of nature"
President Trump and the Rev. Jesse Jackson, who died Tuesday at the age of 84, knew each other for decades.
Democrats make counteroffer on ICE reforms as DHS shutdown continues
Democrats made their counteroffer on overhauling immigration enforcement on Monday, the latest step in talks to fund the Department of Homeland Security.
Iran calls talks with U.S. "more constructive" as Trump's threat looms
Iran and the U.S. traded threats and warnings even as negotiators sat down to discuss a deal to avert a war, but Tehran says "we now have a clearer path ahead."
HealthWatch
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Measles cases at university in Florida soar to nearly 60
Twenty one states in the U.S. have confirmed cases of measles.
Can TrumpRx help you save money on drugs? Here's what experts say.
The Trump administration's new discounted drug platform, TrumpRx, isn't a game-changer for consumers, health care experts said.
Moderna says FDA refuses its application for new mRNA flu vaccine
The Food and Drug Administration is refusing to consider Moderna's application for a new flu vaccine made with mRNA technology, the company said.
What to know about a new study on coffee, tea and dementia risk
CBS News medical contributor Dr. Céline Gounder said the results of the study on coffee drinkers having lower risk of dementia should be taken "with a massive grain of salt."
Thousands of mothers were flagged to police over flawed drug tests at childbirth
The Marshall Project found more than 70,000 cases referred to law enforcement over allegations of substance use during pregnancy — and that's a significant undercount.
World
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Belgium accuses U.S. envoy of disinformation for antisemitism claim
Belgian authorities call the U.S. ambassador's intervention in the case of three Jewish religious figures "dangerous disinformation."
Epstein survivor tells CBS News how she was trafficked, and assaulted
Juliette Bryant says not long after meeting Jeffrey Epstein, he assaulted her, and she realized, "this is not a modeling opportunity, I've been kidnapped."
Iran calls talks with U.S. "more constructive" as Trump's threat looms
Iran and the U.S. traded threats and warnings even as negotiators sat down to discuss a deal to avert a war, but Tehran says "we now have a clearer path ahead."
Russia hammers Ukraine again as U.S. brokers 3rd round of peace talks
The U.S. is brokering a 3rd round of Russia-Ukraine talks, but there's little hope of a breakthrough to end the deadliest war on European soil in 80 years.
Bobsledder Elana Meyers Taylor, 41, wins gold in 5th Olympic appearance
Elana Meyers Taylor has won her first Olympic gold in women's monobob, and she made history as the oldest American woman to do it at the Winter Games.
Entertainment
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Entertainment
Oscar-winning actor Robert Duvall dies at 95
Oscar-winning actor Robert Duvall died on Sunday at the age of 95. Duvall starred in classics like "The Godfather" and "Apocalypse Now." Vladimir Duthiers looks back at his career.
Robert Duvall dies at 95
Robert Duvall, known for his roles in "The Godfather," "Apocalypse Now" and more, has died at 95, his wife announced in a social media post Monday. CBS News correspondent Shanelle Kaul has more.
Robert Duvall, Oscar winner who starred in "The Godfather," dies at age 95
Robert Duvall was in such classics as "The Godfather," "To Kill a Mockingbird," "M*A*S*H," "The Great Santini" and "Tender Mercies."
Stephen A. Smith: Always up for a debate
The high-profile ESPN and SiriusXM commentator and bestselling author is a combative and colorful voice on sports. But now, with a weekly political show in which he interviews government leaders, he is raising eyebrows in Washington, too.
Stephen A. Smith: Always up for a debate
High-profile ESPN and SiriusXM commentator and bestselling author Stephen A. Smith is a combative and colorful voice on sports. But now, with a weekly political show, in which he interviews government leaders, he is gaining notice in Washington, too. Smith talks with "Sunday Morning" national correspondent Robert Costa about his journey and whether he might soon be on a debate stage.
Technology
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Technology
Potential impacts of AI
Matt Shumer joins "CBS Mornings" to discuss his now viral article, "Something Big Is Happening." He writes that AI's "capability for massive disruption could be here by the end of this year." Shumer explains why he wrote the article, and his message to concerned readers.
Viral essay urges people to prepare for AI
If you've been on social media this week, you've likely seen an ominous warning about artificial intelligence in your feed: "Something big is happening." An essay from the CEO of an AI company, Matt Shumer, likens the current moment to February 2020, right before the start of COVID. Nate Soares, co-author of "If Anyone Builds It, Everyone Dies," joins to discuss.
How AI powered robots are helping small farms
From labor shortages to environmental impacts, farmers are looking to AI to help revolutionize the agriculture industry. One California startup, Farm-ng, is tapping into the power of AI and robotics to perform a wide range of tasks, including seeding, weeding and harvesting.
Amazon ends Flock partnership after backlash over Super Bowl ad
Amazon's Ring unit touted a "search party" service in its Super Bowl ad, but one critic called the app a "surveillance nightmare."
FTC warns Apple's Tim Cook over alleged political bias in Apple News app
The Federal Trade Commission sent a letter to Tim Cook one day after President Trump circulated a report raising questions about Apple News' practices.
Science
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How Washington's crossing of the Delaware presaged a changing world
On the evening of Christmas 1776, Gen. George Washington surprised the King's forces by leading the Continental Army in a surprise crossing of a near-frozen Delaware River - a watershed military maneuver that dramatized a changing America, and a changing climate.
These United States: George Washington and climate change
On the evening of Christmas 1776, Gen. George Washington surprised the King's forces by leading the Continental Army in an unanticipated crossing of a near-frozen Delaware River. Environmental correspondent David Schechter looks at how Washington's watershed military maneuver dramatized both a changing America, and a changing climate.
Impact of climate change on Winter Olympics
The Winter Olympics in Milan need artificial snow due to climate change and warmer weather. Athletes say man-made snow makes terrain more difficult and unpredictable. Rob Marciano reports on its impact.
Scientists "quite surprised" to find one polar bear population thriving
After decades monitoring polar bears in Norway's far north, researchers say the animals have proven incredibly adaptable, but there are no guarantees for the future.
Mysterious dark matter seen in new map of distant galaxies
Dark matter doesn't absorb or give off light so scientists can't study it directly. But they can observe how its gravity warps and bends the star stuff around it.
Crime
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No DNA match in database from profile recovered during Nancy Guthrie search
The DNA profile was recovered during the investigation into the disappearance of Nancy Guthrie in Arizona.
"Signal sniffer" deployed in Guthrie search
Investigators deployed a "signal sniffer" device to help pinpoint Nancy Guthrie's location using her pacemaker as the search for the mother of "Today" host Savannah Guthrie enters its third week. CBS News' Jonathan Vigliotti has more.
Sheriff rules out family in Guthrie case
As the search for Nancy Guthrie continues, the Pima County sheriff for the first time is officially ruling out her family members, including siblings and spouses, as possible suspects. Meanwhile, investigators are also using a device known as a "signal sniffer" to try to detect transmissions from Guthrie's pacemaker. Jonathan Vigliotti reports.
Key evidence in the Nancy Guthrie case
Pima County Sheriff Chris Nanos said Nancy Guthrie's family members and their spouses have been cleared as possible suspects in her disappearance. This comes as more details emerge about potential evidence in the case. CBS News' Jonathan Vigliotti reports.
Hillary Clinton on Epstein files handling
Former Secretary of State Hillary Clinton, who is being pressured to testify on what she knows about Jeffrey Epstein's dealings, is accusing the Trump administration of a cover-up over the Justice Department's handling of the Epstein files release. CBS News' Natalie Brand reports.
Space
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Fresh crew arrives at International Space Station to boost numbers back to 7
The Crew 12 docking came one month after a previous crew had to return to Earth early due to a medical issue.
SpaceX launches crew to ISS
NASA and SpaceX launched a new mission to the International Space Station with four crew members on board to replace the team that returned last month due to a medical issue with one member. Mark Strassmann has more.
SpaceX launches space station crew on 8-month mission
The two-woman, two-man crew is replacing four other station fliers who came home early last month due to a medical issue one was having.
NASA, SpaceX mission prepares for launch
NASA and SpaceX say they have completed their final reviews and are ready to launch a crewed mission to the International Space Station on Friday. Retired NASA astronaut Leroy Chiao joins "The Daily Report" to discuss.
ULA rocket has booster problem while launching classified Space Force payloads
A United Launch Alliance Vulcan rocket carrying classified Space Force payloads suffered a booster problem but apparently made an otherwise "nominal" ascent to space, the company said.
Latest Galleries
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Notable Deaths in 2026
A look back at the esteemed personalities who've left us this year, who'd touched us with their innovation, creativity and humanity.
Evidence in the Barbara Kendhammer case
Does the evidence show a cover-up, or was Todd Kendhammer wrongfully convicted for the murder of his wife?
The life & near death of prizefighter Christy Salters-Martin
Christy Salters-Martin dominated in the boxing ring but faced her toughest challenger at home.
Timeline: The disappearance of George Smith
Family seeks answers in death of newlywed who disappeared in 2005 while on Mediterranean honeymoon cruise.
Who is Alix Tichelman?
Meet the tattooed beauty charged in the death of Google executive Forrest Hayes.
Latest CBS News Videos
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Latest CBS News Videos
Democrats send DHS counteroffer to White House
Democrats have sent a counteroffer for immigration enforcement reforms to the White House and Republicans as the partial government shutdown continues. CBS News congressional correspondent Nikole Killion reports.
NAACP president remembers Jesse Jackson
NAACP President and CEO Derrick Johnson joined CBS News to share his thoughts on Jesse Jackson, the civil rights icon who died Tuesday morning at 84.
Al Sharpton reacts to Jesse Jackson's death
Rev. Al Sharpton spoke to reporters on Tuesday following the news of civil rights leader Rev. Jesse Jackson's death. CBS News' Ed O'Keefe has more.
Trump remembers Jesse Jackson
President Trump posted on social media about civil rights leader Rev. Jesse Jackson's death, calling him "a good man" and "a force of nature like few others before him." CBS News' Ed O'Keefe has more.
U.S. bobsledder Elana Meyers Taylor wins gold
Elana Meyers Taylor, the most decorated U.S. female bobsledder, won her first gold medal on Monday, making history as the oldest Winter Olympian to win gold in an individual event. CBS News' Kelly O'Grady has more.