A statement released by MTV Networks on Friday says "Hope for Haiti" will be shown at 8 p.m. EST.
Networks showing the telethon are ABC, CBS, NBC, Fox, CNN, BET, the CW, HBO, MTV, VH1 and CMT. It will also be available internationally.
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Haitian-born entertainer Wyclef Jean will helm the show from New York, and George Clooney will host the Los Angeles part. CNN's Anderson Cooper will be in Haiti.
MTV says there will be musical performances and celebrity appearances. No other talent was announced.
The show will benefit Jean's Yele Haiti Foundation, as well as UNICEF, Oxfam America, Partners in Health, and the Red Cross.