A run for the presidency "is something I would certainly look at," Trump told Reuters. "You know why? I'm unhappy with the way things are going in America."
Trump gave the telephone interview before making a breakfast speech at the "Politics & Eggs" forum at St. Anselm College in Manchester, New Hampshire - an event that tends to feature presidential hopefuls. Trump did not directly address the idea of a running for office during the speech.
New Hampshire traditionally holds the nation's first presidential nominating primaries and is a regular stop for White House aspirants.
He told Reuters he was interested in the idea of personally undoing the legacy of President Barack Obama, who he said had made a "big mistake" with the Affordable Care Act, popularly known as Obamacare, and had done too little to shore up the American economy.
In his speech, Trump said that Christie - widely seen as a potential Republican presidential candidate in 2016 - was "one email away from disaster" after revelations that four days of massive traffic jams on the George Washington Bridge were caused by an act of apparent political payback.
"The thing is he's fired ... people. I don't know what they are going to say, or what emails they are going to produce. It's a tough situation for him," Trump said. "I would have thought Chris would do well (as a candidate). He still could do well, but now it's going to be tougher."
Trump - who made a fortune building skyscrapers and running casinos and now hosts U.S. reality TV show "The Apprentice" - had also toyed with the idea of running for the 2012 Republican nomination but pulled out months before the primary, saying he was not ready to leave the private sector.
He has long been a vocal critic of Obama and made waves after demanding proof the president was born in the United States. The White House released Obama's birth certificate in 2011 showing he was born in Hawaii.
Trump said he believed Obama's handling of the launch of healthcare reform - the president's signature domestic policy achievement which has been fraught with early glitches – would help Republicans during this year's midterm elections.
"It is going to be a tremendous factor going into November and it is going to have a devastating impact on the Democrats," Trump said.
He said he also believes Obama has not done enough to keep the United States competitive in the global economy, and faulted him for his handling of Iraq, Aghanistan, and Syria.
"We used to be the smart ones on the block, now we're the dummies," Trump said.
Trump has also hinted he could run for governor of New York in 2014, claiming he has a $200 million war chest available for a campaign if he chooses to challenge Democratic incumbent Andrew Cuomo.