4. Changes in appearance
istockphoto
According to Tirado it can be difficult to tell when someone is high on opioids, but the most common physical signs include "pinpoint pupils" (pupils that stay constricted, even in dim room light); sudden itching of the arms, stomach or legs; drooping eyes; flushing of the face and neck; head nodding; intense calm; and slurred speech.
When a person is experiencing painkiller withdrawal, they may show frequent yawning, runny nose, dilated pupils, sudden trips to the bathroom (nausea, vomiting, and diarrhea), joint pain (especially in the back and legs), "flu-like" feelings, and severe insomnia.









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