By

Monica DyBuncio /

CBS News/ March 16, 2012, 10:21 AM


Marie, 62, lives in New York and began smoking in high school. Diagnosed with Buerger's disease in her forties, Marie has undergone amputations of part of her right foot, her left leg, and several fingertips.

Brandon, 31, lives in North Dakota and began smoking at age 15. At 18, he was diagnosed with Buerger's, which resulted in the amputation of both his legs and several fingertips.

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