According to a jailhouse interview with the Dutch newspaper De Telegraff, van der Sloot says that he confessed only because he was intimidated during interrogation and had been promised a transfer back to the Netherlands.
De Telegraaf: "I Was Framed" (in Dutch)
The 22-year-old primary suspect in the murder of Stephany Flores is now saying he didn't know what he was signing, that he was tricked and was scared when he confessed, "Early Show" co-anchor Erica Hill reported.
But van der Sloot isn't the only person who may not be so sure anymore.
His own mother has spoken out for the first time since his arrest in Peru.
CBS News correspondent Betty Nguyen reported on "The Early Show" Monday that van der Sloot's mother, Anita van der Sloot, has spoken to a Dutch newspaper and says her son suffers from mental problems and needs psychiatric help. But even more shocking is that she is quoted in the same report saying that he may have had something to do with the death of Stephany Flores.
Anita van der Sloot told the paper, "I now believe that Joran may have indeed done something to Stephany in Peru. Maybe in a burst of anger? I don't know."
She won't even visit her own son in jail.
Anita van der Sloot also told the publication, "..If he killed Stephany, he'll have to pay the price. I won't visit him in his cell. I cannot embrace him."
She said the two spoke on the phone just after Flores' murder. She told him, "You're being searched. A girl is dead. Where are you?"
Joran van der Sloot reportedly replied, "It's not Stephany, is it? No, not Stephany."
His mother told the newspaper, "I told him he had to turn himself in."
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Anita van der Sloot also claims her son refused treatment at a mental institution in the Netherlands right before the Flores' murder. She says "my son is sick in his head."
Legal experts say a confession and surveillance video of him with Flores just before she was murdered will make for a convincing case.
CBS News Legal Analyst Trent Copeland says, "This case is moving forward in Peru. He will stand trial and I don't think the Perivian authorities are going to let him go."
Nguyen added on "The Early Show" that if the insanity defense works and he is convicted of the alleged crime, Joran van der Sloot would only be looking at three to six years in prison. However, if there is evidence linking him to a sexual assault as well as murder, he could be facing 35 years.
CBS News Legal Analyst Jack Ford said on "The Early Show" that van der Sloot's confession isn't easily recanted. He said, like in the American justice system, his confession can be used against him if a court finds legitimacy in his confession.
But Ford said van der Sloot can claim he is a pathological liar.
"There are some interesting arguments," Ford said. "But just because he says no now, doesn't mean it can't be used against him down the road."
As for Anita van der Sloot's statements to the newspaper, Ford said it might be part of a strategy by Joran van der Sloot's defense team.
Ford said, "If I am his lawyer, the first thing I'm saying if I'm speaking to family and friends, and if he is indeed confessing to this as he did in the beginning, 'We need to find something,' and maybe that something is an insanity defense."
Ford added that just because someone is diagnosed with a mental disease or a personality defect disorder, it doesn't mean they are criminally insane.
If someone is claiming they are criminally insane, Ford said, they must show they have a disease and also show that because of that disease they didn't know what they were doing and/or they didn't know that it was wrong.
"There's much more you need," Ford said.
Van der Sloot, who is also suspected in the disappearance of Natalee Holloway, is scheduled to be interrogated today by Peruvian authorities.
Ford said during the Peruvian interrogation van der Sloot must answer the questions he's asked, unlike in the U.S., where someone can decline to answer.
But will he tell the truth?
Ford said van der Sloot can lie or tell the truth, but if he does lie and the prosecution can prove he's lying, "that's not going to help him down the road."