The transfer cuts the number of men now held at the isolated U.S. Naval station in southeast Cuba to about 275, a decline of nearly a third in the last year.
About 136 of the 759 people detained at Guantanamo since 2002 have been Saudi, the second-largest group after Afghans. The vast majority have been repatriated - despite the fact that more than 90 percent are still considered a terrorist threat.
The U.S. agreed to return the men with the understanding that Saudi Arabia will mitigate that risk, partly through a state program to reintegrate former detainees into civilian life, said Navy Cmdr. Jeffrey Gordon, a Defense Department spokesman.
Their detention has been a source of strain with Riyadh, a close U.S. ally.
"We will continue to work with the international community in our efforts to further reduce the population at Guantanamo, while at the same time taking prudent measures designed to protect the public," Gordon said.
Three Saudis have committed suicide inside the camp, which holds foreigners suspected of links to terrorism, al Qaeda and the Taliban.