"She's had enough," one source told RadarOnline. "She's ending the marriage."
RadarOnline broke the story Tuesday.
Bullock has been dogged by tabloid reports since internet rumors surfaced that Bullock's husband of five years split after tattoo model Michelle "Bombshell" McGee claimed she had an affair with James - partly while Bullock was making her Oscar-winning film "The Blind Side."
Soon after, more alleged mistresses came out. , a tattooed stripper, told Star Magazine, she slept with James, and Brigitte Daguerre, a Los Angeles-based photographer and fetish model was tied to James by TMZ.
MORE ON CRIMESIDER
March 22, 2010 - Jesse James' Ex-Wife, Porn Star Janine Lindemulder, Wants Custody of Daughter