The national security adviser underwent uterine fibroid embolization at Georgetown University Hospital, and it appeared to be successful with no complications, said Jim Wilkinson, a deputy national security adviser.
"The surgery was successful and she is resting comfortably," Wilkinson said.
Uterine fibroid embolization blocks blood flow to fibroids, noncancerous tumors in the uterus. It is meant to shrink the growths by injecting small particles into the blood vessels that "feed" the fibroids to cut off their blood supply. For some women it is an alternative to hysterectomy. Radiologist Dr. James Spies performed the procedure, Wilkinson said.
Rice was scheduled to stay overnight at the hospital and go home Saturday. She could return to work as early as Monday, Wilkinson said.
Mr. Bush announced on Tuesday that Rice, 50, will succeed Secretary of State Colin Powell. Her nomination must be confirmed by the Senate.
Mr. Bush traveled Friday to Chile for an international summit. He brought Steve Hadley, Rice's deputy and the president's pick to head the National Security Council if Rice is confirmed.