Last Updated Dec 17, 2013 8:11 PM EST
The shooting occurred at the offices of the Center for Advanced Medicine and Neurology of Nevada. located on the sprawling campus of the Renown Regional Medical Center, authorities said. Initial reports said the shooting occurred at the hospital.
CBS affiliate KTVN reported the first emergency call came at around 2:05 p.m. for an incident at the Professional Medical Building on East 2nd Street.
"We have two people confirmed deceased in the building, two others injured," Reno Police Deputy Police Chief Tim Robison told a news conference.
He said the incident was over and the building was "secure and safe."
No motive was given. Robison said police believe the gunman acted alone.
Gail Powell, a spokeswoman for the Nevada Department of Public Safety, said one of the wounded was a female doctor. No other information was available.
Gov. Brian Sandoval tweeted that he and his wife "send our thoughts and prayers to those affected by today's tragedy," adding that he and his staff was monitoring the situation.