The ad will air in about 20 states, including Arkansas, Colorado, and Nebraska, and is targeted to areas where lawmakers are undecided on reform efforts.
The ad shows a balloon being inflated with words "tax increases, swelling deficits, government control" written on it. A voiceover notes that the Congressional Budget Office predicts the deficit will grow $239 billion if one form of health care reform is passed.
The balloon eventually bursts, as the voiceover says: "Tell Congress, 'Let's slow down and reform health care the right way.'"
R. Bruce Josten, executive vice president of Chamber of Commerce, told the Associated Press that the ad will be one of the most visible ad-based criticisms of Mr. Obama's health care plan.
Opponents of health reform have been heavily outspent in advertising by Mr. Obama's supporters this year, according to the AP.