The president will have the procedure at Walter Reed Army Medical Center and, while there, will also visit soldiers wounded in Iraq, White House Press Secretary Scott McClellan said.
Bush, 57, is having the test on the advice of his White House physician, Dr. Richard Tubb. MRI, or magnetic resonance imaging, is a body-scanning technique that reveals internal organs in 3-D detail.
In September, Mr. Bush said he believed he had a meniscus tear — a common injury to the cartilage that lines the inside surfaces of the knee.
McClellan said that because of the pain in Mr. Bush's right knee, the avid jogger has run only occasionally in recent months. Instead, Mr. Bush has been using an elliptical trainer and water jogging to get aerobic exercise.
"He's still working out regularly," McClellan said. "He's showing the wear and tear of someone who is active and someone who is his age."