A person familiar with the list of attendees confirmed Wednesday that the young billionaire is expected to attend.
Obama is spending part of Thursday and Friday on the West Coast. The White House says Thursday's session will focus on creating jobs. On Friday, Obama travels to Hillsboro, Ore., to visit Intel Corp. to draw attention to the role of education in preparing Americans for new high-tech jobs.
The White House says the meeting is part of the president's ongoing dialogue with the business community.
Zuckerberg is the 26-year-old wunderkind behind Facebook. The social networking site has more than 500 million users worldwide.