Amanda Knox: I'm overwhelmed right now

SEATTLE - In her first press conference since having her murder conviction overturned in Italy, Amanda Knox spoke briefly about her return home before breaking down in tears.

"I'm a little overhwlemed right now," Knox said, adding that looking down from the airplane on her flight home was surreal.

"Thanks to everyone who believed in me, who has defended me, who supported my family," Knox said before tearing up. "My family's the most important thing right now and i just want to go be with them."

Knox then appeared to be too overcome with emotions to continue.

After Italian prisoners gave her a boisterous send-off, Amanda Knox made her way home to America on earlier Tuesday, holing up with family on the upper deck of a jetliner to Seattle as she enjoyed her first full day of freedom since her murder conviction was reversed.

Knox's mom, Edda Mellas, told the crowd before Knox spoke that "It's because of the letters and the calls and just the amazing support we've received from people all over the world" that they've been able to get by.

Friends and family who held spaghetti dinners, bowling events and concerts to raise money for Knox's defense waited anxiously for her plane to touch down -- a moment that took four years to happen.

"We all are as happy as can be. I can't tell you how long we've been looking forward to this day," her grandmother Elisabeth Huff told The Associated Press outside her home in West Seattle, a tight-knit community a few miles across Elliott Bay from downtown.

"WELCOME HOME AMANDA," read the marquee at a record store in the neighborhood where Knox grew up. Another welcome sign was hung at her father's house. A bar offered half-price drinks to celebrate her acquittal.

Knox's life turned around dramatically Monday when an Italian appeals court threw out her conviction in the sexual assault and fatal stabbing of her British roommate. The case played out under an international spotlight, and on Tuesday a courtroom picture of Knox crying after the verdict was read appeared on the front pages of newspapers in Italy, the U.S., Britain and around the world.

The court's decision, fueled by doubts over DNA evidence, stunned the victim's family and angered the prosecution, which insists that she was among three people who killed 21-year-old Meredith Kercher. But for Huff, "it was like the weight of the world had gone."

"Now I can look forward to sleeping at night. We were just jumping with joy," she told The Associated Press outside her Seattle home Tuesday afternoon.

Now free, Amanda Knox flies back to U.S.

Knox, 24, left Perugia's Capanne prison Monday night amid cheers that a companion compared to those at a soccer stadium.

Hundreds of inmates -- most of them in the men's wing -- shouted "Amanda, ciao!" and "Freedom!" as she walked into the central courtyard, said Corrado Maria Daclon, head of the Italy-US Foundation, which championed Knox's cause.

"They were screaming like crazy," said Daclon, who accompanied Knox in her first hours of freedom. Daclon said Knox jumped a little for joy and waved to the prisoners.

Amanda Knox friend: She feels like she's flying

She was soon on her way home, protected by the darkened windows of a Mercedes that led her out of the prison in the middle of the night, and then Tuesday morning to Rome's Leonardo da Vinci airport.

"During the trip from Perugia to Rome, Amanda was serene," said Daclon, who was with Knox in the car.

She flew from Rome to London, where she took a direct British Airways flight to Seattle, flying business class with full-length seat and menu options including champagne, smoked salmon and prawn salad.

Video: Hometown supporter awaits Knox arrival

At least nine members of media organizations were on board, but a flight attendant blocked them from the plane's secluded upper deck "to preserve the privacy" of passengers.

The attendant, quoting a Knox family member, said media were not allowed to contact Knox or her family on the flight but were welcome to attend a news conference late Tuesday afternoon at Seattle-Tacoma International Airport. It was unclear whether Knox herself would speak then.

"Those who wrote, those who defended me, those who were close, those who prayed for me," Knox wrote in a letter released just hours before leaving Italy, "I love you."

Knox thanked those Italians "who shared my suffering and helped me survive with hope," in a letter to the Italy-US Foundation, which seeks to promote ties between the two countries.

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Timeline of the Amanda Knox case
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Knox was a University of Washington student studying abroad in Perugia when Kercher was killed in 2007.

"We've spent a lot of time waiting," her uncle Michael Huff said in Seattle. "We're planning a big hug. We'll see day to day how it goes. She's going to have to get acclimated. She's a strong kid."

Kerchner's family said during an emotional news conference Tuesday that they were back to "square one."

"If those two are not the guilty parties, then who are the guilty people?" asked Lyle Kercher, a brother of the victim.

Prosecutor Giuliano Mignini expressed disbelief at the innocent verdicts of Knox and her former boyfriend, Raffaele Sollecito. He said he will appeal to Italy's highest criminal court after receiving the reasoning behind the acquittals, due within 90 days.

"Let's wait and we will see who was right. The first court or the appeal court," Mignini told The Associated Press on Tuesday. "This trial was done under unacceptable media pressure."

Italian prosecutors vow appeal of Knox verdict

Prosecutors maintain that Knox, Sollecito and another man killed Kercher during a lurid, drug-fueled sex game. Knox was sentenced to 26 years in prison and Sollecito received 25, but the prosecution's case was blown apart by a DNA review ordered during the appeals trial that discredited crucial genetic evidence.

Prosecutors maintain that Knox's DNA was found on the handle of a kitchen knife believed to be the murder weapon, and that Kercher's DNA was found on the blade. They said Sollecito's DNA was on the clasp of Kercher's bra as part of a mix of evidence that also included the victim's genetic profile.

But an independent review -- ordered at the request of the defense, which had always disputed those findings -- found that police conducting the investigation had made glaring errors in evidence-collecting. The two experts said below-standard testing and possible contamination raised doubts over the attribution of DNA traces, both on the blade and on the bra clasp, which was collected from the crime scene 46 days after the murder.

The review was crucial to throwing out the convictions because no motive has emerged and witness testimony was contradictory.

Kerchers "back at square one" after Knox verdict

The highest court will determine whether any procedures were violated. The hearing generally takes one day in Rome, and defendants are not required to attend.

If the highest court overturns the acquittal, prosecutors would be free to request Knox's extradition to Italy to finish whatever remained of a sentence. It would be up to the government to decide whether to make the formal extradition request.

One conviction in the slaying still stands: that of Ivory Coast native Rudy Hermann Guede. His lawyer said Tuesday he will seek a retrial.

Guede was convicted in a separate fast-track procedure and saw his sentence cut to 16 years in his final appeal. He says he is innocent, though he admits being in the house the night of the murder.

Defense lawyers maintain that Guede was the sole killer, while prosecutors say that bruises and a lack of defensive wounds on Kercher's body prove that there was more than one aggressor holding her into submission. However, they could never quite explain how Knox and Sollecito, who had been dating for less than a week, would be involved in an extreme sexual scenario with somebody only one of them barely knew.

The highest court, in upholding Guede's conviction, said he had not acted alone. But it did not name Knox and Sollecito as Guede's accomplices, saying it was not up to the court to determine that.

Kercher's family was perplexed. The decision "obviously raises further questions," Lyle Kercher said.