Chicago Cubs starting lineup for 2025 home opener game against San Diego Padres

The Chicago Cubs will face off against the San Diego Padres in their 2025 home opener at Wrigley Field Friday.

MORE: See Chicago Cubs full 2025 MLB schedule

First pitch is at 1:20 p.m.

We now know the starting lineup for both teams. Check them out below.

Starting lineups for Cubs home opener:

Chicago Cubs

1. Ian Happ, LF
2. Kyle Tucker, RF
3. Seiya Suzuki, DH
4. Michael Busch, 1B
5. Dansby Swanson , SS
6. Nico Hoerner, 2B
7. Pete Crow-Armstrong, CF
8. Matt Shaw, 3B
9. Miguel Amaya, C
10. Shota Imanaga, P

San Diego Padres

1. Fernando Tatis, Jr., RF
2. Luis Arraez, 1B
3. Manny Machado, 3B
4. Xander Bogaerts, SS
5. Jackson Merrill, CF
6. Yuli Gurriel, DH
7. Jake Cronenworth, 2B
8. Brandon Lockridge, LF
9. Martin Maldonado, C
   
10. Randy Vasquez, P

This is the first in at three-game series against the Padres at home for the Cubs. After that, they take on the Texas Rangers at Wrigley for another three games. 

• Chicago Cubs
• Baseball
• San Diego Padres
• Wrigley Field